The association between prenatal pyrethroids exposure and children's health - current research.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-11-06 Epub Date: 2024-09-10 DOI:10.13075/ijomeh.1896.02445

Agnieszka Jankowska, Maja Ścieszko, Alicja Polańska, Alexandra Jerzyńska, Jolanta Dominowska, Agnieszka Brzozowska

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引用次数: 0

Abstract

Exposure to pyrethroids, a widely used agricultural, forestry, and household insecticide, is a major public health concern due to its potential health effects on children. The aim of this review was to summarize the current knowledge of the effects of prenatal exposure to pyrethroids on the course and outcome of pregnancy, health status, and neurobehavioural development of children. A systematic and comprehensive search of the PubMed, Web of Science, and Scopus databases was conducted during January-February 2024. The review included original articles published in peerreviewed English-language journals since 2015. Based on keywords, 198 studies were identified and screened for eligibility. Ultimately, the review analyzed 25 articles including 16 that assessed the effects of prenatal exposure to pyrethroids on children's neurobehavioural development, 3 studies that assessed the effects on the course and outcome of pregnancy, and further 3 focused on respiratory disease. In addition, 1 study analyzed the development of obesity and 2 studies examined the effects on children's growth, weight and body composition in early childhood. In conclusion, there is considerable uncertainty about the adverse effects of prenatal exposure to pyrethroids on children's health. The strongest evidence has been reported for neurobehavioural development although results are also inconsistent. Further research is needed to understand the mechanisms of action and health effects of pyrethroids in susceptible populations. Int J Occup Med Environ Health. 2024;37(4):381-402.

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产前接触拟除虫菊酯与儿童健康之间的关系--当前研究。

拟除虫菊酯是一种广泛应用于农业、林业和家庭的杀虫剂，由于其对儿童健康的潜在影响，拟除虫菊酯的暴露已成为一个重大的公共卫生问题。本综述旨在总结产前接触拟除虫菊酯对妊娠过程和结果、儿童健康状况和神经行为发育影响的现有知识。2024 年 1 月至 2 月期间，对 PubMed、Web of Science 和 Scopus 数据库进行了系统而全面的检索。综述包括自 2015 年以来在同行评审的英文期刊上发表的原创文章。根据关键词确定了 198 项研究，并进行了资格筛选。最终，综述分析了 25 篇文章，其中 16 篇评估了产前接触拟除虫菊酯对儿童神经行为发育的影响，3 篇评估了对妊娠过程和结果的影响，另外 3 篇侧重于呼吸系统疾病。此外，1 项研究分析了肥胖症的发展，2 项研究探讨了对幼儿期儿童生长、体重和身体成分的影响。总之，产前接触拟除虫菊酯对儿童健康的不良影响还存在很大的不确定性。最有力的证据是关于神经行为发育的报告，尽管结果也不一致。要了解除虫菊酯对易感人群的作用机制和健康影响，还需要进一步的研究。Int J Occup Med Environ Health.2024;37(4).

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.