Differences in Drug Poisonings Among Those Who Identify as Transgender Compared to Cisgender: An Analysis of the Toxicology Investigators Consortium (ToxIC) Core Registry, United States 2017-2021.

IF 3.2 4区 医学 Q2 PHARMACOLOGY & PHARMACY
Clinical therapeutics Pub Date : 2024-12-01 Epub Date: 2024-09-19 DOI:10.1016/j.clinthera.2024.08.018
Kristine Magnusson, Emily Glidden, Desiree Mustaquim, Laura E Welder, Erin K Stokes, Gillian A Beauchamp, Marna R Greenberg, Kim Aldy, Richard J Mazzaccaro, Beth A Careyva, Judith N Sabino, Derek J Fikse, Katelyn McLain, Alexandra M Amaducci
{"title":"Differences in Drug Poisonings Among Those Who Identify as Transgender Compared to Cisgender: An Analysis of the Toxicology Investigators Consortium (ToxIC) Core Registry, United States 2017-2021.","authors":"Kristine Magnusson, Emily Glidden, Desiree Mustaquim, Laura E Welder, Erin K Stokes, Gillian A Beauchamp, Marna R Greenberg, Kim Aldy, Richard J Mazzaccaro, Beth A Careyva, Judith N Sabino, Derek J Fikse, Katelyn McLain, Alexandra M Amaducci","doi":"10.1016/j.clinthera.2024.08.018","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>In this manuscript, the abbreviation TG is defined as persons who identify as transgender, GNC is defined as persons who identify as gender nonconforming, and CG is defined as persons who identify as cisgender. TG and GNC (e.g., nonbinary), are those whose gender identity and sex assigned at birth do not align, as opposed to CG. This study describes drug poisonings among TG, GNC, and CG captured in the Toxicology Investigators Consortium (ToxIC) Core Registry during 2017-2021.</p><p><strong>Methods: </strong>Authors conducted a secondary data analysis of medical toxicology physician consultations involving intentional exposures (i.e., use with the knowledge of the exposed person) within the ToxIC Core Registry from 2017 through 2021. Demographic characteristics, exposure intent, and reported drug classes are reported by gender identity and sex assigned at birth.</p><p><strong>Findings: </strong>From a total of 15,800 medical toxicology consultations, 213 (1.3%) involved both TG (n = 187, 1.2%) and GNC (n = 26, 0.2%), and 15,587 (98.7%) involved CG. Among TG, 128 (68.8%) were transgender men, 58 (31.2%) transgender women. Sixty-two percent of TG/GNC (n = 132) and 34.8% of CG (n = 5,428) were aged ≤18 years. Reported intent for exposure (i.e., self-harm and misuse/harmful use) differed proportionally across both sexes assigned at birth and gender identity among transgender men and cisgender men.</p><p><strong>Implications: </strong>In the ToxIC Core Registry, the consultations varied proportionally by age group across TG/GNC and CG, with more than half of TG/GNC aged ≤18 years. The proportion of consultations also varied by intent across TG/GNC and CG. Further research to delineate differences between TG/GNC and CG could increase knowledge in prevention, assessment, and treatment of drug poisonings in this population.</p>","PeriodicalId":10699,"journal":{"name":"Clinical therapeutics","volume":" ","pages":"953-959"},"PeriodicalIF":3.2000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical therapeutics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.clinthera.2024.08.018","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/19 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose: In this manuscript, the abbreviation TG is defined as persons who identify as transgender, GNC is defined as persons who identify as gender nonconforming, and CG is defined as persons who identify as cisgender. TG and GNC (e.g., nonbinary), are those whose gender identity and sex assigned at birth do not align, as opposed to CG. This study describes drug poisonings among TG, GNC, and CG captured in the Toxicology Investigators Consortium (ToxIC) Core Registry during 2017-2021.

Methods: Authors conducted a secondary data analysis of medical toxicology physician consultations involving intentional exposures (i.e., use with the knowledge of the exposed person) within the ToxIC Core Registry from 2017 through 2021. Demographic characteristics, exposure intent, and reported drug classes are reported by gender identity and sex assigned at birth.

Findings: From a total of 15,800 medical toxicology consultations, 213 (1.3%) involved both TG (n = 187, 1.2%) and GNC (n = 26, 0.2%), and 15,587 (98.7%) involved CG. Among TG, 128 (68.8%) were transgender men, 58 (31.2%) transgender women. Sixty-two percent of TG/GNC (n = 132) and 34.8% of CG (n = 5,428) were aged ≤18 years. Reported intent for exposure (i.e., self-harm and misuse/harmful use) differed proportionally across both sexes assigned at birth and gender identity among transgender men and cisgender men.

Implications: In the ToxIC Core Registry, the consultations varied proportionally by age group across TG/GNC and CG, with more than half of TG/GNC aged ≤18 years. The proportion of consultations also varied by intent across TG/GNC and CG. Further research to delineate differences between TG/GNC and CG could increase knowledge in prevention, assessment, and treatment of drug poisonings in this population.

变性人与同性人的药物中毒差异:2017-2021年美国毒理学研究者联盟(ToxIC)核心登记分析》。
目的:在本手稿中,缩写 TG 定义为认定为跨性别者,GNC 定义为认定为性别不符者,CG 定义为认定为顺性性别者。TG 和 GNC(如非二元)是指性别认同与出生时的性别不一致的人,而 CG 则是指性别认同与出生时的性别不一致的人。本研究描述了毒理学调查者联盟(ToxIC)核心注册中心在2017-2021年间记录的TG、GNC和CG的药物中毒情况:作者对 2017 年至 2021 年 ToxIC 核心注册表中涉及故意暴露(即在被暴露者知情的情况下使用)的医学毒理学医生咨询进行了二次数据分析。人口统计学特征、暴露意图和报告的药物类别按性别身份和出生时分配的性别进行报告:在总共 15,800 次医学毒理学咨询中,213 次(1.3%)涉及 TG(n = 187,1.2%)和 GNC(n = 26,0.2%),15,587 次(98.7%)涉及 CG。在 TG 中,128 人(68.8%)为变性男性,58 人(31.2%)为变性女性。62% 的 TG/GNC (n = 132)和 34.8% 的 CG(n = 5428)年龄在 18 岁以下。在变性男性和双性恋男性中,报告的接触意图(即自我伤害和误用/有害使用)在出生时的性别分配和性别认同方面存在比例差异:在 ToxIC 核心注册表中,TG/GNC 和 CG 的咨询比例因年龄组而异,超过一半的 TG/GNC 年龄在 18 岁以下。在 TG/GNC 和 CG 中,咨询比例也因意图而异。进一步研究 TG/GNC 和 CG 之间的差异,可以增加该人群预防、评估和治疗药物中毒的知识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Clinical therapeutics
Clinical therapeutics 医学-药学
CiteScore
6.00
自引率
3.10%
发文量
154
审稿时长
9 weeks
期刊介绍: Clinical Therapeutics provides peer-reviewed, rapid publication of recent developments in drug and other therapies as well as in diagnostics, pharmacoeconomics, health policy, treatment outcomes, and innovations in drug and biologics research. In addition Clinical Therapeutics features updates on specific topics collated by expert Topic Editors. Clinical Therapeutics is read by a large international audience of scientists and clinicians in a variety of research, academic, and clinical practice settings. Articles are indexed by all major biomedical abstracting databases.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信