Development of a 3D-printed phantom for total skin electron therapy dose assessment

IF 2 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Andrew Lee, Zaid Alkhatib, Mounir Ibrahim, Broderick McCallum-Hee, Joshua Dass, Matthew Fernandez de Viana, Pejman Rowshanfarzad
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引用次数: 0

Abstract

Purpose

Total skin electron therapy (TSET) is a complex radiotherapy technique, posing challenges in commissioning and quality assurance (QA), especially due to significant variability in patient body shapes. Previous studies have correlated dose with factors such as obesity index, height, and gender. However, current treatment planning systems cannot simulate TSET plans, necessitating heavy reliance on QA methods using standardized anthropomorphic phantoms and in-vivo dosimetry. Given the relatively few studies on rotational techniques, comprehensive data in commissioning could streamline the process.

Methods

Developing a full-body phantom would enable a more thorough TSET commissioning process, including testing for position-specific dose distributions and comprehensive measurements across all body surfaces, unlike the typical torso-only phantoms. This was created using digital modeling software, fabricated using 3D-printing FDM technology, and filled with tissue-equivalent gelatine. The phantom was positioned at an SSD of 340 cm and irradiated with a standard rotational TSET plan using the 6E HDTSE mode on a Varian TrueBeam linac at gantry angles of ± 18° from the horizontal. The dose was measured at over 50 points across the surface using Gafchromic EBT3 film.

Results

Dose distributions were generally consistent with existing literature values from in-vivo dosimetry, with several position-specific differences identified, including the hands and scalp compared to conventional positions. Hotspots were observed for the mid-dorsum of the foot and nose, with areas under 80% of the dose identified as the soles of the feet, perineum, vertex of the scalp, top of the shoulder, and palm of the hand. Additionally, analysis using an interpolated dose heatmap found that 90% of the pixel area received a dose within 10% of the prescribed dose, indicating good uniformity with the commissioned technique.

Conclusions

With high agreement with the current literature, a 3D-printed phantom proves effective for measuring doses in areas typically unmeasurable in TSET commissioning.

Abstract Image

开发用于皮肤电子治疗总剂量评估的 3D 打印模型
目的全皮肤电子疗法(TSET)是一种复杂的放射治疗技术,给调试和质量保证(QA)带来了挑战,特别是由于患者体形的显著差异。以往的研究表明,剂量与肥胖指数、身高和性别等因素相关。然而,目前的治疗计划系统无法模拟 TSET 计划,因此必须高度依赖使用标准化拟人模型和体内剂量测定的质量保证方法。与典型的仅有躯干的模型不同,开发一个全身模型可以实现更全面的 TSET 调试过程,包括测试特定体位的剂量分布和全身表面的全面测量。该模型使用数字建模软件创建,采用三维打印 FDM 技术制造,并填充了相当于组织的明胶。将模型放置在 340 厘米的固态硬盘上,在瓦里安 TrueBeam 直列加速器上使用 6E HDTSE 模式以标准旋转 TSET 计划进行辐照,龙门与水平面的夹角为 ± 18°。使用 Gafchromic EBT3 胶片测量了整个表面 50 多个点的剂量。结果剂量分布与现有文献中的体内剂量测定值基本一致,但发现了几个特定位置的差异,包括手部和头皮与传统位置的差异。在脚背中部和鼻子处观察到了热点,剂量低于 80% 的区域被确定为脚底、会阴、头皮顶点、肩顶和手掌。此外,使用内插剂量热图进行分析发现,90% 的像素区域接受的剂量在规定剂量的 10% 以内,这表明调试技术具有良好的一致性。结论3D 打印模型与现有文献高度一致,证明它能有效测量 TSET 调试中通常无法测量的区域的剂量。
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来源期刊
CiteScore
3.60
自引率
19.00%
发文量
331
审稿时长
3 months
期刊介绍: Journal of Applied Clinical Medical Physics is an international Open Access publication dedicated to clinical medical physics. JACMP welcomes original contributions dealing with all aspects of medical physics from scientists working in the clinical medical physics around the world. JACMP accepts only online submission. JACMP will publish: -Original Contributions: Peer-reviewed, investigations that represent new and significant contributions to the field. Recommended word count: up to 7500. -Review Articles: Reviews of major areas or sub-areas in the field of clinical medical physics. These articles may be of any length and are peer reviewed. -Technical Notes: These should be no longer than 3000 words, including key references. -Letters to the Editor: Comments on papers published in JACMP or on any other matters of interest to clinical medical physics. These should not be more than 1250 (including the literature) and their publication is only based on the decision of the editor, who occasionally asks experts on the merit of the contents. -Book Reviews: The editorial office solicits Book Reviews. -Announcements of Forthcoming Meetings: The Editor may provide notice of forthcoming meetings, course offerings, and other events relevant to clinical medical physics. -Parallel Opposed Editorial: We welcome topics relevant to clinical practice and medical physics profession. The contents can be controversial debate or opposed aspects of an issue. One author argues for the position and the other against. Each side of the debate contains an opening statement up to 800 words, followed by a rebuttal up to 500 words. Readers interested in participating in this series should contact the moderator with a proposed title and a short description of the topic
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