Remember oligodendrocytes: Uncovering their overlooked role in Alzheimer's disease.

IF 7.8 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

PLoS Biology Pub Date : 2024-09-12 DOI:10.1371/journal.pbio.3002798

Lena Spieth,Mikael Simons

引用次数: 0

Abstract

Our understanding of Alzheimer's disease (AD) has evolved from focusing solely on neurons to recognizing the role of glia. A recent study in PLOS Biology revealed that oligodendrocytes are an important source of Aβ that impairs neuronal function.

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记住少突胶质细胞：揭示少突胶质细胞在阿尔茨海默病中被忽视的作用

我们对阿尔茨海默病（AD）的认识已经从单纯关注神经元发展到认识到胶质细胞的作用。最近发表在《PLOS Biology》上的一项研究显示，少突胶质细胞是损害神经元功能的 Aβ 的重要来源。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

PLoS Biology 生物-生化与分子生物学

CiteScore

14.40

自引率

2.00%

发文量

359

审稿时长

3 months

期刊介绍： PLOS Biology is an open-access, peer-reviewed general biology journal published by PLOS, a nonprofit organization of scientists and physicians dedicated to making the world's scientific and medical literature freely accessible. The journal publishes new articles online weekly, with issues compiled and published monthly. ISSN Numbers: eISSN: 1545-7885 ISSN: 1544-9173