Increasing our knowledge about the epidemiology of Helicobacter pylori in Nunavik's Inuit population (Québec, Canada) using Qanuilirpitaa? 2017 cross-sectional survey.

IF 1.3 4区医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

International Journal of Circumpolar Health Pub Date : 2024-09-16 DOI:10.1080/22423982.2024.2398864

Julie Ducrocq,Benoit Lévesque,Gaston De Serres,Véronique Boiteau,Cedric P Yansouni,Jean-François Proulx,Denis Talbot

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引用次数: 0

Abstract

Helicobacter pylori is a bacterium that may colonise and proliferate in human stomachs, leading invariably to chronic inflammation and, to a lesser extent, to peptic ulcers and cancer. The main objective of this study is to describe the epidemiology surrounding H. pylori in Nunavik's Inuit population using the 2004 and 2017 Health Surveys. Estimated prevalences were 70.9% for bacterial colonisation using a stool antigens test (SAT), 72.5% for anti-H. pylori antibodies, 12.7% for faecal occult blood in participants aged ≥ 50 and respectively of 28.4%, 11.2% and 2.4% for a prior diagnosis of colonisation, gastritis and peptic ulcer in the medical charts, with under five cases of gastric cancer reported. Variables associated with higher SAT+ prevalence were the number of household members (prevalence ratio [PR] = 1.03) and age (quadratic relationship), whereas mainly drinking municipal (PR = 0.84) and natural water (PR = 0.72) compared to bottled water, and increasing alcohol consumption (PR = 0.96) were associated with reduced prevalence. Despite current regional guidelines targeting high risk individuals in the context of high prevalence, Nunavik's health authorities must remain vigilant by following gastric cancer incidence and the rapid evolution of guidelines, while considering local realities.

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通过 Qanuilirpitaa? 2017 年横断面调查，增加我们对努纳维克因纽特人（加拿大魁北克省）幽门螺杆菌流行病学的了解。

幽门螺杆菌是一种可在人类胃部定植和增殖的细菌，通常会导致慢性炎症，并在较小程度上导致消化性溃疡和癌症。本研究的主要目的是利用 2004 年和 2017 年的健康调查，描述努纳维克因纽特人中幽门螺杆菌的流行病学情况。通过粪便抗原检测（SAT），估计细菌定植率为 70.9%，抗幽门螺杆菌抗体为 72.5%，年龄≥50 岁的参与者粪便隐血率为 12.7%，病历中先前诊断为定植、胃炎和消化性溃疡的比例分别为 28.4%、11.2% 和 2.4%，报告的胃癌病例不足 5 例。与 SAT+ 患病率较高相关的变量是家庭成员数量（患病率比 [PR] = 1.03）和年龄（二次方关系），而与瓶装水相比，主要饮用市政水（PR = 0.84）和天然水（PR = 0.72）以及饮酒量增加（PR = 0.96）与患病率降低相关。尽管目前的地区指南针对的是高发病率下的高危人群，但努纳维克的卫生当局必须保持警惕，在考虑当地实际情况的同时，关注胃癌的发病率和指南的快速发展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Circumpolar Health 医学-公共卫生、环境卫生与职业卫生

CiteScore

2.10

自引率

15.40%

发文量

审稿时长

6-12 weeks

期刊介绍： The International Journal of Circumpolar Health is published by Taylor & Francis on behalf of the Circumpolar Health Research Network [CircHNet]. The journal follows the tradition initiated by its predecessor, Arctic Medical Research. The journal specializes in circumpolar health. It provides a forum for many disciplines, including the biomedical sciences, social sciences, and humanities as they relate to human health in high latitude environments. The journal has a particular interest in the health of indigenous peoples. It is a vehicle for dissemination and exchange of knowledge among researchers, policy makers, practitioners, and those they serve. International Journal of Circumpolar Health welcomes Original Research Articles, Review Articles, Short Communications, Book Reviews, Dissertation Summaries, History and Biography, Clinical Case Reports, Public Health Practice, Conference and Workshop Reports, and Letters to the Editor.