{"title":"A Top Solvent-Additive-Ionization Technique Combination for Pesticides Direct Infusion MS Analysis","authors":"Darko Anđelković, Milica Branković","doi":"10.1002/jms.5092","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>The leading type of ionization technique in mass spectrometry analyses is the ionization at atmospheric pressure. The aim of this study was to assess ESI and APCI ionization efficiency of pesticides introduced to the MS source in four organic phases, non-doped and doped with formic acid and ammonium formate. Ionization efficiency in modified ESI and APCI, applying in-source sample heating, was also assessed. The study was primarily designed to support non-chromatography-based mass spectrometry pesticides analysis by the direct infusion technique. Evaluation of analysis performances such as calibration performances, detectability, and sensitivity should indicate a top solvent-additive-source combination, leading to the highest ionization efficiency and lowest analytes detection limits.</p>\n </div>","PeriodicalId":16178,"journal":{"name":"Journal of Mass Spectrometry","volume":"59 10","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Mass Spectrometry","FirstCategoryId":"92","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jms.5092","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
The leading type of ionization technique in mass spectrometry analyses is the ionization at atmospheric pressure. The aim of this study was to assess ESI and APCI ionization efficiency of pesticides introduced to the MS source in four organic phases, non-doped and doped with formic acid and ammonium formate. Ionization efficiency in modified ESI and APCI, applying in-source sample heating, was also assessed. The study was primarily designed to support non-chromatography-based mass spectrometry pesticides analysis by the direct infusion technique. Evaluation of analysis performances such as calibration performances, detectability, and sensitivity should indicate a top solvent-additive-source combination, leading to the highest ionization efficiency and lowest analytes detection limits.
质谱分析中的主要电离技术类型是常压电离。本研究旨在评估在四种有机相（未掺杂和掺杂甲酸和甲酸铵）中引入质谱源的农药的 ESI 和 APCI 电离效率。此外，还评估了采用源内样品加热的改良 ESI 和 APCI 电离效率。这项研究的主要目的是支持采用直接注入技术的非色谱法质谱农药分析。对分析性能（如校准性能、可检测性和灵敏度）的评估应表明，最佳的溶剂-添加剂-源组合可实现最高的电离效率和最低的分析物检测限。
期刊介绍：
The Journal of Mass Spectrometry publishes papers on a broad range of topics of interest to scientists working in both fundamental and applied areas involving the study of gaseous ions.
The aim of JMS is to serve the scientific community with information provided and arranged to help senior investigators to better stay abreast of new discoveries and studies in their own field, to make them aware of events and developments in associated fields, and to provide students and newcomers the basic tools with which to learn fundamental and applied aspects of mass spectrometry.
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