Artificial intelligence-assisted quantitative CT parameters in predicting the degree of risk of solitary pulmonary nodules.

IF 4.9 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Long Jiang,Yang Zhou,Wang Miao,Hongda Zhu,Ningyuan Zou,Yu Tian,Hanbo Pan,Weiqiu Jin,Jia Huang,Qingquan Luo
{"title":"Artificial intelligence-assisted quantitative CT parameters in predicting the degree of risk of solitary pulmonary nodules.","authors":"Long Jiang,Yang Zhou,Wang Miao,Hongda Zhu,Ningyuan Zou,Yu Tian,Hanbo Pan,Weiqiu Jin,Jia Huang,Qingquan Luo","doi":"10.1080/07853890.2024.2405075","DOIUrl":null,"url":null,"abstract":"INTRODUCTION\r\nArtificial intelligence (AI) shows promise for evaluating solitary pulmonary nodules (SPNs) on computed tomography (CT). Accurately determining cancer invasiveness can guide treatment. We aimed to investigate quantitative CT parameters for invasiveness prediction.\r\n\r\nMETHODS\r\nPatients with stage 0-IB NSCLC after surgical resection were retrospectively analysed. Preoperative CTs were evaluated with specialized software for nodule segmentation and CT quantification. Pathology was the reference for invasiveness. Univariate and multivariate logistic regression assessed predictors of high-risk SPN.\r\n\r\nRESULTS\r\nThree hundred and fifty-five SPN were included. On multivariate analysis, CT value mean and nodule type (ground glass opacity vs. solid) were independent predictors of high-risk SPN. The area under the curve (AUC) was 0.811 for identifying high-risk nodules.\r\n\r\nCONCLUSIONS\r\nQuantitative CT measures and nodule type correlated with invasiveness. Software-based CT assessment shows potential for noninvasive prediction to guide extent of resection. Further prospective validation is needed, including comparison with benign nodules.","PeriodicalId":8371,"journal":{"name":"Annals of medicine","volume":null,"pages":null},"PeriodicalIF":4.9000,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/07853890.2024.2405075","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0

Abstract

INTRODUCTION Artificial intelligence (AI) shows promise for evaluating solitary pulmonary nodules (SPNs) on computed tomography (CT). Accurately determining cancer invasiveness can guide treatment. We aimed to investigate quantitative CT parameters for invasiveness prediction. METHODS Patients with stage 0-IB NSCLC after surgical resection were retrospectively analysed. Preoperative CTs were evaluated with specialized software for nodule segmentation and CT quantification. Pathology was the reference for invasiveness. Univariate and multivariate logistic regression assessed predictors of high-risk SPN. RESULTS Three hundred and fifty-five SPN were included. On multivariate analysis, CT value mean and nodule type (ground glass opacity vs. solid) were independent predictors of high-risk SPN. The area under the curve (AUC) was 0.811 for identifying high-risk nodules. CONCLUSIONS Quantitative CT measures and nodule type correlated with invasiveness. Software-based CT assessment shows potential for noninvasive prediction to guide extent of resection. Further prospective validation is needed, including comparison with benign nodules.
人工智能辅助定量 CT 参数在预测单发肺结节风险程度中的应用。
引言 人工智能(AI)有望评估计算机断层扫描(CT)上的单发肺结节(SPN)。准确判断癌症的侵袭性可以指导治疗。我们旨在研究用于侵袭性预测的定量 CT 参数。方法回顾性分析了手术切除后的 0-IB 期 NSCLC 患者。使用专业软件对术前 CT 进行评估,以进行结节分割和 CT 定量。病理学是侵袭性的参考标准。结果纳入了 355 个 SPN。在多变量分析中,CT 值平均值和结节类型(磨玻璃不透明与实性)是高风险 SPN 的独立预测因素。鉴定高风险结节的曲线下面积(AUC)为 0.811。基于软件的 CT 评估显示了无创预测指导切除范围的潜力。需要进一步进行前瞻性验证,包括与良性结节进行比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Annals of medicine
Annals of medicine 医学-医学:内科
CiteScore
4.90
自引率
0.00%
发文量
292
审稿时长
3 months
期刊介绍: Annals of Medicine is one of the world’s leading general medical review journals, boasting an impact factor of 5.435. It presents high-quality topical review articles, commissioned by the Editors and Editorial Committee, as well as original articles. The journal provides the current opinion on recent developments across the major medical specialties, with a particular focus on internal medicine. The peer-reviewed content of the journal keeps readers updated on the latest advances in the understanding of the pathogenesis of diseases, and in how molecular medicine and genetics can be applied in daily clinical practice.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信