Stimulus-responsive MOF–hydrogel composites: Classification, preparation, characterization, and their advancement in medical treatments

IF 2.1 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Open Chemistry Pub Date : 2024-08-22 DOI:10.1515/chem-2024-0061

Jia En Toh, Choy Sin Lee, Wei Huei Lim, Mallikarjuna Rao Pichika, Bing Wei Chua

引用次数: 0

Abstract

Metal–organic frameworks (MOFs) have attracted chemical and material research interests in recent years due to their incredibly prominent properties and unique structures. Although MOFs have many unique characteristics, including tunable pore structures and functionality, their application performances are hindered by their powdered crystalline state, intrinsic fragility, poor processability, and stability. Recent studies have shown that the incorporation of MOFs into hydrogel outperforms the MOFs in their crystalline state. This article presents the current development of stimulus-responsive MOF–hydrogel composites in terms of synthesis of MOF and preparation of MOF–hydrogel, characterization, and advancement of stimulus-responsive MOF–hydrogel composite in drug delivery and wound management. The article also discusses prospective study directions, delineating potential avenues for further exploration and innovation in this dynamic field.

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刺激响应型 MOF-水凝胶复合材料：分类、制备、表征及其在医疗中的应用

近年来，金属有机框架（MOFs）以其令人难以置信的突出特性和独特结构吸引了化学和材料研究人员的兴趣。尽管 MOFs 具有许多独特的特性，包括可调孔结构和功能性，但其粉末结晶状态、内在脆性、加工性差和稳定性阻碍了它们的应用性能。最新研究表明，将 MOFs 加入水凝胶中的效果优于结晶状态的 MOFs。本文从 MOF 的合成、MOF-水凝胶的制备、表征以及刺激响应型 MOF-水凝胶复合材料在药物输送和伤口处理方面的应用等方面介绍了刺激响应型 MOF-水凝胶复合材料的发展现状。文章还讨论了前瞻性研究方向，为这一充满活力的领域的进一步探索和创新划定了潜在途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open Chemistry CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

3.80

自引率

4.30%

发文量

审稿时长

6 weeks

期刊介绍： Open Chemistry is a peer-reviewed, open access journal that publishes original research, reviews and short communications in the fields of chemistry in an ongoing way. The central goal is to provide a hub for researchers working across all subjects to present their discoveries, and to be a forum for the discussion of the important issues in the field. The journal is the premier source for cutting edge research in fundamental chemistry and it provides high quality peer review services for its authors across the world. Moreover, it allows for libraries everywhere to avoid subscribing to multiple local publications, and to receive instead all the necessary chemistry research from a single source available to the entire scientific community.