PSMA PET in brain metastases: navigating diagnostic challenges– a thorough exploration

IF 2.3 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical and Translational Imaging Pub Date : 2024-09-03 DOI:10.1007/s40336-024-00655-y

Lorenzo Jonghi-Lavarini, Federico Fallanca, Gino Pepe, Carolina Bezzi, Samuele Ghezzo, Arturo Chiti, Paola Mapelli, Maria Picchio

引用次数: 0

Abstract

PSMA imaging is gaining importance in the field of oncology, both for diagnostic and therapeutic purposes. In this review, we aimed to highlight the significance of detecting brain metastases from prostate carcinoma before the onset of symptoms, also considering potential pitfalls and false-positive findings. To emphasize this aspect, we present a case report in which the use of an extended field of view to the vertex allowed to the localization of brain lesions before the onset of symptoms. The present clinical report describe the rare case of brain metastases from prostate carcinoma detected by [¹⁸F]F-PSMA-1007 PET/CT.

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PSMA PET 在脑转移瘤中的应用：应对诊断挑战--深入探讨

PSMA 成像在肿瘤学领域的重要性与日俱增，既可用于诊断，也可用于治疗。在这篇综述中，我们旨在强调在症状出现之前检测前列腺癌脑转移灶的重要性，同时考虑潜在的误区和假阳性结果。为了强调这一点，我们提交了一份病例报告，在该病例中，由于使用了扩大视野至顶点的方法，在症状出现前就确定了脑部病灶的位置。本临床报告描述了通过[18F]F-PSMA-1007 PET/CT发现前列腺癌脑转移的罕见病例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical and Translational Imaging Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

3.60

自引率

4.80%

发文量

期刊介绍： Clinical and Translational Imaging is an international journal that publishes timely, up-to-date summaries on clinical practice and translational research and clinical applications of approved and experimental radiopharmaceuticals for diagnostic and therapeutic purposes. Coverage includes such topics as advanced preclinical evidence in the fields of physics, dosimetry, radiation biology and radiopharmacy with relevance to applications in human subjects. The journal benefits a readership of nuclear medicine practitioners and allied professionals involved in molecular imaging and therapy.