Stability of the Ionic Parameters of a Nonlocal FitzHugh-Nagumo Model of Cardiac Electrophysiology

IF 1.2 4区 数学 Q2 MATHEMATICS, APPLIED
Narjess Ben Abid, Mostafa Bendahmane, Moncef Mahjoub
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引用次数: 0

Abstract

This paper presents an inverse problem of identifying two ionic parameters of a nonlocal reaction-diffusion system in cardiac electrophysiology modelling. We used a nonlocal FitzHugh-Nagumo monodomain model which describes the electrical activity in cardiac tissue with the diffusion rate assumed to depend on the total electrical potential in the heart. We established at first, the global Carleman estimate adapted to nonlocal diffusion to obtain our main result which is the uniqueness and the Lipschitz stability estimate for two ionic parameters \((k,\gamma )\).

心脏电生理学非局部 FitzHugh-Nagumo 模型离子参数的稳定性
本文介绍了在心脏电生理学建模中识别非局部反应-扩散系统的两个离子参数的逆问题。我们使用非局部 FitzHugh-Nagumo 单域模型来描述心脏组织中的电活动,并假定扩散率取决于心脏中的总电势。我们首先建立了适应非局部扩散的全局卡勒曼估计,从而得到了我们的主要结果,即两个离子参数 \((k,\gamma )\) 的唯一性和 Lipschitz 稳定性估计。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Acta Applicandae Mathematicae
Acta Applicandae Mathematicae 数学-应用数学
CiteScore
2.80
自引率
6.20%
发文量
77
审稿时长
16.2 months
期刊介绍: Acta Applicandae Mathematicae is devoted to the art and techniques of applying mathematics and the development of new, applicable mathematical methods. Covering a large spectrum from modeling to qualitative analysis and computational methods, Acta Applicandae Mathematicae contains papers on different aspects of the relationship between theory and applications, ranging from descriptive papers on actual applications meeting contemporary mathematical standards to proofs of new and deep theorems in applied mathematics.
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