Modeling the dynamics of Covid-19 in Japan: employing data-driven deep learning approach

IF 3.1 3区 计算机科学 Q2 COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE
S. Patrick Nelson, R. Raja, P. Eswaran, J. Alzabut, G. Rajchakit
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Abstract

This paper aims to build the SVIHRD model for COVID-19 and it also simultaneously conduct stability and numerical analysis on the transmission of COVID-19. Here we do a mathematical analysis for the SVIHRD model, which involves positivity, boundedness, uniqueness, and proving both global and local stability. In the process of numerical simulation, we use real-world data for COVID-19 cases in Japan. An important feature presents in this paper, is that we replace the usual numerical solving technique for obtaining the parameters with a Physics Informed Neural Network (PINN). This PINN needs an order of time instances as input and the number of Susceptible (S), Vaccinated (V), Infected (I), Hospitalized (H), Recovered (R), and Death (D) people per time instances to learn specific parameters of the model using loss functions. We developed three different PINN setups-the baseline model, configuration-I, and configuration-II-to explore and optimize these parameters for modeling COVID-19 dynamics in Japan. During the validation process, we evaluated how well the learned parameters from these three PINN architectures predicted real infection data for the next two months. The baseline model, with four hidden layers and 32 neurons each, performed well with an \(R^{2}\) value of 0.8038 and a Wilcoxon signed-rank test p value of 0.001556, closely matching actual infection data. A sensitivity analysis of the baseline model’s parameters showed that the vaccination rate \(\sigma\) is the most sensitive.

Abstract Image

日本 Covid-19 动态建模:采用数据驱动的深度学习方法
本文旨在建立 COVID-19 的 SVIHRD 模型,并同时对 COVID-19 的传播进行稳定性和数值分析。在此,我们对 SVIHRD 模型进行了数学分析,包括正相关性、有界性、唯一性,并证明了全局和局部稳定性。在数值模拟过程中,我们使用了日本 COVID-19 案例的实际数据。本文的一个重要特点是,我们用物理信息神经网络(PINN)取代了通常的数值求解技术来获取参数。该 PINN 需要一阶时间实例作为输入,以及每个时间实例中的易感 (S)、接种 (V)、感染 (I)、住院 (H)、康复 (R) 和死亡 (D) 人数,从而利用损失函数学习模型的特定参数。我们开发了三种不同的 PINN 设置(基线模型、配置-I 和配置-II)来探索和优化这些参数,以模拟日本的 COVID-19 动态。在验证过程中,我们评估了从这三种 PINN 架构中学到的参数对未来两个月真实感染数据的预测效果。基线模型有四个隐藏层,每个隐藏层有 32 个神经元,表现良好,\(R^{2}\) 值为 0.8038,Wilcoxon 符号秩检验 p 值为 0.001556,与实际感染数据非常接近。对基线模型参数的敏感性分析表明,疫苗接种率是最敏感的。
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来源期刊
International Journal of Machine Learning and Cybernetics
International Journal of Machine Learning and Cybernetics COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE-
CiteScore
7.90
自引率
10.70%
发文量
225
期刊介绍: Cybernetics is concerned with describing complex interactions and interrelationships between systems which are omnipresent in our daily life. Machine Learning discovers fundamental functional relationships between variables and ensembles of variables in systems. The merging of the disciplines of Machine Learning and Cybernetics is aimed at the discovery of various forms of interaction between systems through diverse mechanisms of learning from data. The International Journal of Machine Learning and Cybernetics (IJMLC) focuses on the key research problems emerging at the junction of machine learning and cybernetics and serves as a broad forum for rapid dissemination of the latest advancements in the area. The emphasis of IJMLC is on the hybrid development of machine learning and cybernetics schemes inspired by different contributing disciplines such as engineering, mathematics, cognitive sciences, and applications. New ideas, design alternatives, implementations and case studies pertaining to all the aspects of machine learning and cybernetics fall within the scope of the IJMLC. Key research areas to be covered by the journal include: Machine Learning for modeling interactions between systems Pattern Recognition technology to support discovery of system-environment interaction Control of system-environment interactions Biochemical interaction in biological and biologically-inspired systems Learning for improvement of communication schemes between systems
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