Paracetamol sensing with a flexible graphene paper electrode modified with MnCo2O4

IF 2.8 4区生物学 Q3 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Journal of chemical technology and biotechnology Pub Date : 2024-08-28 DOI:10.1002/jctb.7739

Murad Shafiyev, Elif Erçarıkcı, Kader Dağcı Kıranşan, Ezgi Topçu

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引用次数: 0

Abstract

BACKGROUND

The design of new-generation flexible sensors for medical applications has gained considerable interest in the research community in recent past years. Herein, a free-standing flexible electrode was developed for the electrochemical determination of Paracetamol (PC). This graphene-based paper electrode was prepared using graphene and MnCo₂O₄ dispersion with a mold-casting method followed by chemical reduction. The morphology and structure of our flexible paper electrode (MnCo₂O₄/GP) were characterized by scanning electron microscopy, energy-dispersive, X-ray diffraction, X-ray photoelectron, and Raman spectroscopy.

RESULTS

The as-prepared flexible MnCo₂O₄/GP showed outstanding sensing performance for PC, as compared to GP, due to the excellent electrochemical properties of MnCo₂O₄. The proposed sensor exhibited a wide linear range of 4.64–1000 μM for electrochemical determination of PC with a low detection limit of 1.39 μM. Furthermore, MnCo₂O₄/GP was successfully applied for PC syrup and tablets with good accuracy results.

CONCLUSIONS

For the first time, the present study demonstrated the fabrication and utilization of MnCo₂O₄-modified graphene paper to develop a flexible and sensitive electrode for monitoring PC. © 2024 The Author(s). Journal of Chemical Technology and Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry (SCI).

Abstract Image

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用钴酸锰修饰的柔性石墨烯纸电极传感扑热息痛

背景近年来，用于医疗应用的新一代柔性传感器的设计在研究界引起了极大的兴趣。在此，我们开发了一种用于电化学测定扑热息痛（PC）的独立柔性电极。这种基于石墨烯的纸电极是用石墨烯和 MnCo2O4 分散液通过模铸法制备的，然后进行了化学还原。通过扫描电子显微镜、能量色散、X 射线衍射、X 射线光电子学和拉曼光谱对柔性纸电极（MnCo2O4/GP）的形态和结构进行了表征。所提出的传感器在电化学测定 PC 方面具有 4.64-1000 μM 的宽线性范围和 1.39 μM 的低检测限。此外，MnCo2O4/GP 还成功地应用于 PC 糖浆和片剂的检测，并获得了良好的准确度结果。© 2024 作者姓名化学技术与生物技术期刊》由 John Wiley & Sons Ltd 代表化学工业学会 (SCI) 出版。

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来源期刊

Journal of chemical technology and biotechnology 工程技术-工程：化工

CiteScore

7.00

自引率

5.90%

发文量

268

审稿时长

1.7 months

期刊介绍： Journal of Chemical Technology and Biotechnology(JCTB) is an international, inter-disciplinary peer-reviewed journal concerned with the application of scientific discoveries and advancements in chemical and biological technology that aim towards economically and environmentally sustainable industrial processes.