Comparative analysis of axial and radial mechanical properties of cortical bone using nanoindentation

IF 0.9 4区 材料科学 Q4 MATERIALS SCIENCE, MULTIDISCIPLINARY
Rongchang Fu, Huaiyue Zhang, Xiaozheng Yang, Zhaoyao Wang
{"title":"Comparative analysis of axial and radial mechanical properties of cortical bone using nanoindentation","authors":"Rongchang Fu, Huaiyue Zhang, Xiaozheng Yang, Zhaoyao Wang","doi":"10.2140/jomms.2024.19.669","DOIUrl":null,"url":null,"abstract":"<p>We investigate differences in mechanical properties between anatomical regions and bearing surfaces of cortical bone at the microscale. </p><p> Eight samples were prepared from fresh femoral bones, and then loaded onto the four sides of the anatomical region, including the front, back, inside, and outside, as well as the axial and radial directions. Nanoindentation testing was performed on each sample using six indentations to acquire load-depth curves. The curves were then analyzed to determine the elastic modulus and hardness of the materials. Statistical analysis was subsequently conducted to assess the data distribution and variability. Finite element simulation may have been utilized to establish a more comprehensive mechanical behavior model. </p><p> The mechanical properties of cortical bone varied significantly across various anatomical regions and bearing surfaces, the elastic modulus and hardness of the anterior and medial sides were significantly greater compared with those of the posterior and lateral sides. The elastic modulus in the axial direction was significantly higher relative to that in the radial direction by 21.94% <math display=\"inline\" xmlns=\"http://www.w3.org/1998/Math/MathML\"><mo stretchy=\"false\">(</mo><mi>p</mi><mo> ⁡<!--FUNCTION APPLICATION--> </mo><!--nolimits-->\n<mo>&lt;</mo> <mn>0</mn><mo>.</mo><mn>0</mn><mn>0</mn><mn>1</mn><mo stretchy=\"false\">)</mo></math>. The hardness increased by 13.3% <math display=\"inline\" xmlns=\"http://www.w3.org/1998/Math/MathML\"><mo stretchy=\"false\">(</mo><mi>p</mi><mo> ⁡<!--FUNCTION APPLICATION--> </mo><!--nolimits-->\n<mo>=</mo> <mn>0</mn><mo>.</mo><mn>0</mn><mn>3</mn><mo stretchy=\"false\">)</mo></math>. The elastic modulus and hardness of cortical bone increased in the same direction, showing a strong positive correlation (<math display=\"inline\" xmlns=\"http://www.w3.org/1998/Math/MathML\"><msup><mrow><mi> R</mi><mo> ⁡<!--FUNCTION APPLICATION--> </mo><!--nolimits--></mrow><mrow><mn>2</mn></mrow></msup>\n<mo>=</mo> <mn>0</mn><mo>.</mo><mn>8</mn><mn>1</mn><mn>7</mn></math>, <math display=\"inline\" xmlns=\"http://www.w3.org/1998/Math/MathML\"><mi> p</mi><mo> ⁡<!--FUNCTION APPLICATION--> </mo><!--nolimits-->\n<mo>&lt;</mo> <mn>0</mn><mo>.</mo><mn>0</mn><mn>0</mn><mn>1</mn></math>). Under the same conditions, the stresses in the axial direction of the cortical bone exceeds those in the radial direction. </p>","PeriodicalId":50134,"journal":{"name":"Journal of Mechanics of Materials and Structures","volume":"44 1","pages":""},"PeriodicalIF":0.9000,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Mechanics of Materials and Structures","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.2140/jomms.2024.19.669","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

Abstract

We investigate differences in mechanical properties between anatomical regions and bearing surfaces of cortical bone at the microscale.

Eight samples were prepared from fresh femoral bones, and then loaded onto the four sides of the anatomical region, including the front, back, inside, and outside, as well as the axial and radial directions. Nanoindentation testing was performed on each sample using six indentations to acquire load-depth curves. The curves were then analyzed to determine the elastic modulus and hardness of the materials. Statistical analysis was subsequently conducted to assess the data distribution and variability. Finite element simulation may have been utilized to establish a more comprehensive mechanical behavior model.

The mechanical properties of cortical bone varied significantly across various anatomical regions and bearing surfaces, the elastic modulus and hardness of the anterior and medial sides were significantly greater compared with those of the posterior and lateral sides. The elastic modulus in the axial direction was significantly higher relative to that in the radial direction by 21.94% (p < 0.001). The hardness increased by 13.3% (p = 0.03). The elastic modulus and hardness of cortical bone increased in the same direction, showing a strong positive correlation ( R 2 = 0.817, p < 0.001). Under the same conditions, the stresses in the axial direction of the cortical bone exceeds those in the radial direction.

利用纳米压痕技术比较分析皮质骨的轴向和径向力学性能
我们在微观尺度上研究了皮质骨的解剖区域和承载表面之间的力学性能差异。 我们从新鲜股骨头中制备了八个样本,然后将其加载到解剖区域的四个面上,包括正面、背面、内部和外部,以及轴向和径向方向。对每个样本进行纳米压痕测试,使用六个压痕获取载荷-深度曲线。然后对曲线进行分析,以确定材料的弹性模量和硬度。随后进行统计分析,以评估数据分布和可变性。有限元模拟可用于建立更全面的机械行为模型。 皮质骨的机械性能在不同的解剖区域和承载面之间存在显著差异,前侧和内侧的弹性模量和硬度明显高于后侧和外侧。轴向的弹性模量比径向的弹性模量高出 21.94% (p < 0.001)。硬度增加了 13.3% (p = 0.03)。皮质骨的弹性模量和硬度沿同一方向增加,显示出很强的正相关性 ( R 2= 0.817, p < 0.001)。在相同条件下,皮质骨轴向应力超过径向应力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Journal of Mechanics of Materials and Structures
Journal of Mechanics of Materials and Structures 工程技术-材料科学:综合
CiteScore
1.40
自引率
0.00%
发文量
8
审稿时长
3.5 months
期刊介绍: Drawing from all areas of engineering, materials, and biology, the mechanics of solids, materials, and structures is experiencing considerable growth in directions not anticipated a few years ago, which involve the development of new technology requiring multidisciplinary simulation. The journal stimulates this growth by emphasizing fundamental advances that are relevant in dealing with problems of all length scales. Of growing interest are the multiscale problems with an interaction between small and large scale phenomena.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信