Investigation of Production Possibility of Medical Isotope 155Tb on Cyclotron C18/18

IF 0.5 4区物理与天体物理 Q4 PHYSICS, MULTIDISCIPLINARY

Journal of Contemporary Physics (Armenian Academy of Sciences) Pub Date : 2024-09-09 DOI:10.1134/S1068337224700038

R. V. Avetisyan, A. G. Barseghyan, Yu. H. Gharibyan, A. V. Gyurjinyan, I. A. Kerobyan, H. A. Mkrtchyan, A. Yu. Petrosyan

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Abstract

The results of the studies on the production of ¹⁵⁵Tb isotope, which is used in theranostic applications for oncological diseases, utilizing the proton beam of the medical cyclotron C18/18 are presented. The measurements of the induced activity were carried out using the activation method, followed by spectrometric analysis. Natural gadolinium was used as the main target. Excitation functions were calculated for the ^natGd(p, xn)¹⁵⁵Tb reactions using TALYS 1.96 and EMPIRE 3.2 theoretical nuclear codes. The measured cross-section values were compared with the results of the theoretical calculations as well as with the experimental data from other works. The experimental value of the integral activity of the radionuclide ¹⁵⁵Tb was compared to the results obtained with the TALYS 1.96 code and with early published data.

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研究在回旋加速器 C18/18 上生产医用同位素 155Tb 的可能性

摘要介绍了利用 C18/18 型医用回旋加速器的质子束生产 155Tb 同位素的研究结果。使用活化法对诱导活性进行了测量，然后进行了光谱分析。天然钆被用作主要靶标。使用 TALYS 1.96 和 EMPIRE 3.2 理论核代码计算了 natGd(p, xn)155Tb 反应的激发函数。测得的截面值与理论计算结果以及其他研究的实验数据进行了比较。放射性核素 155Tb 的积分活度实验值与使用 TALYS 1.96 代码获得的结果以及早期公布的数据进行了比较。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Contemporary Physics (Armenian Academy of Sciences) PHYSICS, MULTIDISCIPLINARY-

CiteScore

1.00

自引率

66.70%

发文量

审稿时长

6-12 weeks

期刊介绍： Journal of Contemporary Physics (Armenian Academy of Sciences) is a journal that covers all fields of modern physics. It publishes significant contributions in such areas of theoretical and applied science as interaction of elementary particles at superhigh energies, elementary particle physics, charged particle interactions with matter, physics of semiconductors and semiconductor devices, physics of condensed matter, radiophysics and radioelectronics, optics and quantum electronics, quantum size effects, nanophysics, sensorics, and superconductivity.