Nina Fattahi, Olga Nilsson, Sverker Svensjö, Joy Roy, Anneli Linné, Rebecka Hultgren
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引用次数: 0
Abstract
Objective: The psychological consequences of being aware of an increased risk of developing abdominal aortic aneurysm as a first-degree relative of a person with abdominal aortic aneurysm are hitherto unexplored. This study investigates the awareness of heritability and anxiety in male and female adult offspring of abdominal aortic aneurysm patients compared to controls. Health-related quality of life among participants with aortic pathology was compared to participants with normal aortic diameters.
Methods: This was a cross-sectional point prevalence study based on the participants examined in the Detecting Abdominal Aortic Aneurysm in First Degree Relatives Trial (DAAAD; 752 adult offspring, 756 matched controls), 2020-2022. Questionnaires about health-related quality of life and study-specific questions regarding awareness of heritability were collected prior to the aortic ultrasound.
Results: Attendance rate was higher among individuals with heredity compared to controls (67% vs. 52%, p < 0.001). Of 1508 adult offspring examined, 65% reported having a close relative with abdominal aortic aneurysm (6% in controls). Female adult offspring reported higher awareness of heritability than controls (38% vs. 12%, p < 0.001), as did males (32% vs. 8%, p < 0.001). A slight majority of participants with awareness reported anxiety (54% of female offspring; 51% of male). There were no measured differences in health-related quality of life between the groups when standard health-related quality of life instruments were used.
Conclusion: The higher-than-expected proportion of adult offspring with awareness of heritability and anxiety about such risk indicates that we fail to communicate risk to this group appropriately via the current channels of information within the healthcare system. This calls for the development of dedicated strategies for improved communication of abdominal aortic aneurysm risk to patients and their next of kin.
目的：作为腹主动脉瘤患者的一级亲属，如果意识到患腹主动脉瘤的风险增加，会产生什么样的心理后果，迄今为止尚未进行过研究。本研究调查了腹主动脉瘤患者的成年男性和女性后代与对照组相比对遗传性和焦虑的认识。将主动脉病变参与者与主动脉直径正常参与者的健康相关生活质量进行了比较：这是一项横断面点流行率研究，以2020-2022年 "检测一级亲属腹主动脉瘤试验"（DAAAD；752名成年后代，756名匹配对照）的参与者为基础。在进行主动脉超声检查前收集了与健康相关的生活质量调查问卷以及与研究相关的对遗传性认识的问题：结果：与对照组相比，遗传病患者的就诊率更高（67% 对 52%，p p p 结论：遗传病患者的就诊率高于预期：成年后代中了解遗传性并对这种风险感到焦虑的比例高于预期，这表明我们未能通过医疗系统内现有的信息渠道向这一群体适当传达风险信息。这就需要制定专门的策略，改善与患者及其近亲的腹主动脉瘤风险沟通。
期刊介绍：
Journal of Medical Screening, a fully peer reviewed journal, is concerned with all aspects of medical screening, particularly the publication of research that advances screening theory and practice. The journal aims to increase awareness of the principles of screening (quantitative and statistical aspects), screening techniques and procedures and methodologies from all specialties. An essential subscription for physicians, clinicians and academics with an interest in screening, epidemiology and public health.
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