Metastatic malignancies in the parotid gland: A retrospective study

IF 2.1 2区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Cranio-Maxillofacial Surgery Pub Date : 2024-11-01 DOI:10.1016/j.jcms.2024.08.007

Michał Gontarz , Marta Urbańska , Jakub Bargiel , Krzysztof Gąsiorowski , Tomasz Marecik , Paweł Szczurowski , Jan Zapała , Grażyna Wyszyńska-Pawelec

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引用次数: 0

Abstract

The aim of this study was to compare treatment modalities, pathological and clinical characteristics, and outcomes in patients with metastasis in a parotid gland.

The medical records of 34 patients who received treatment for metastasis in the parotid gland over a twenty-year period were evaluated. Patients with head and neck cutaneous squamous cell carcinoma (HNcSCC) metastasis were retrospectively reclassified using the P/N and N1S3 staging system.

Patients with neck metastasis showed a significantly poorer prognosis (P = 0.025). Univariate analysis also revealed that extent of parotidectomy and type of neck dissection did not influence recurrence free survival (RFS) and overall survival (OS). When comparing the usefulness of the P/N and S1N3 staging systems, a positive correlation was observed between the P stage and the N1S3 stage in both RFS and OS.

The extent of parotidectomy and concomitant neck dissection is still under discussion. Total parotidectomy and modified radical neck dissection did not improve RFS and OS. N1S3 is a less complex classification and possesses a higher predictive value when compared to the P/N staging system.

查看原文本刊更多论文

腮腺转移性恶性肿瘤：一项回顾性研究。

本研究的目的是比较腮腺转移患者的治疗方式、病理和临床特征以及疗效。研究评估了 34 名腮腺转移患者在 20 年间接受治疗的病历。采用P/N和N1S3分期系统对头颈部皮肤鳞状细胞癌（HNcSCC）转移患者进行了回顾性重新分类。颈部转移的患者预后明显较差（P = 0.025）。单变量分析还显示，腮腺切除范围和颈部切除类型并不影响无复发生存率（RFS）和总生存率（OS）。在比较P/N和S1N3分期系统的实用性时，P分期和N1S3分期在RFS和OS中均呈正相关。腮腺切除术和同时进行的颈部切除术的范围仍在讨论中。腮腺全切除术和改良根治性颈部切除术并不能改善RFS和OS。与P/N分期系统相比，N1S3是一种不那么复杂的分类，具有更高的预测价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Cranio-Maxillofacial Surgery 医学-外科

CiteScore

5.20

自引率

22.60%

发文量

117

审稿时长

70 days

期刊介绍： The Journal of Cranio-Maxillofacial Surgery publishes articles covering all aspects of surgery of the head, face and jaw. Specific topics covered recently have included: • Distraction osteogenesis • Synthetic bone substitutes • Fibroblast growth factors • Fetal wound healing • Skull base surgery • Computer-assisted surgery • Vascularized bone grafts