The association between cam morphology and hip pain in males and females within 10 years: A national prospective cohort study (CHECK)

IF 4.6 2区 医学 Q1 RHEUMATOLOGY
Jinchi Tang , Michiel M.A. van Buuren , Fleur Boel , Noortje S. Riedstra , Myrthe A. van den Berg , Jos Runhaar , Sita Bierma-Zeinstra , Rintje Agricola
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引用次数: 0

Abstract

Objectives

To determine the association between baseline cam morphology and self-reported hip pain assessed at annual visits over a 10-year follow-up period stratified by biological sex. The secondary aim was to study the association between the magnitude of cam morphology and the severity of pain in symptomatic hips.

Methods

The nationwide prospective Cohort Hip and Cohort Knee (CHECK) study includes 1,002 participants aged 45-65 years. Logistic regression with generalized estimating equations were used to determine the strength of the associations between (1) baseline cam morphology (both alpha angle ≥60° and as a continuous measure) and the presence of hip pain at 10 annual follow-up visits and (2) the alpha angle (continuous) and the severity of pain as classified by Numerical Rating Scale at 5-,8-, 9-, and 10-years. The results are expressed as odds ratios (OR), adjusted for age, biological sex (only in the sex-combined group), body mass index, and follow-up Kellgren and Lawrence grade.

Results

In total, 1,658 hips were included at baseline (1,335 female hips (79.2%)). The prevalence of cam morphology was 11.1% among all hips (29.1% in males; 6.4% in females). No association was found between cam morphology at baseline and the presence of hip pain at any follow-up in the female or sex-combined group. In males, only at 5-year follow-up, significant adjusted ORs were observed for the presence of cam morphology (1.77 (95%CI: 1.01-3.09)) and the alpha angle (1.02 (95%CI:1.00-1.04)). No evidence of associations was found between the alpha angle and the severity of hip pain in any of three groups.

Conclusion

Within this study, no consistent associations were found between cam morphology and hip pain at multiple follow-ups. There might be a weak relationship between cam morphology and hip pain in males, while no such relation was found in females. We did not identify an association between the alpha angle and severity of hip pain.

Abstract Image

10年内男性和女性凸轮形态与髋关节疼痛之间的关系:全国前瞻性队列研究(CHECK)。
目的确定基线凸轮形态与在10年随访期内每年就诊时自我报告的髋关节疼痛之间的关系,并按生理性别进行分层。次要目的是研究凸轮形态大小与有症状髋关节疼痛严重程度之间的关系:全国性前瞻性队列髋关节和队列膝关节(CHECK)研究包括 1002 名 45-65 岁的参与者。该研究使用逻辑回归和广义估计方程来确定:(1) 基线凸轮形态(α角≥60°和连续测量)与10次年度随访时出现髋关节疼痛之间的关联强度;(2) α角(连续)与5年、8年、9年和10年时按数字评分量表分类的疼痛严重程度之间的关联强度。结果以几率比(OR)表示,并根据年龄、生理性别(仅在性别合并组中)、体重指数以及随访的凯尔格伦和劳伦斯分级进行了调整:共有 1,658 个髋关节被纳入基线(其中 1,335 个髋关节为女性,占 79.2%)。在所有髋关节中,凸轮变形的发生率为 11.1%(男性为 29.1%;女性为 6.4%)。在女性或性别组合组中,均未发现基线凸轮形态与任何随访中出现的髋关节疼痛之间存在关联。在男性中,只有在5年随访时,才观察到凸轮形态(1.77(95%CI:1.01-3.09))和α角(1.02(95%CI:1.00-1.04))的调整OR值显著。在三个组别中,均未发现α角与髋关节疼痛严重程度之间存在关联的证据:在这项研究中,多次随访均未发现凸轮形态与髋关节疼痛之间存在一致的关联。男性的凸轮形态与髋关节疼痛之间可能存在微弱的关系,而女性则没有这种关系。我们没有发现α角与髋关节疼痛严重程度之间存在关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
9.20
自引率
4.00%
发文量
176
审稿时长
46 days
期刊介绍: Seminars in Arthritis and Rheumatism provides access to the highest-quality clinical, therapeutic and translational research about arthritis, rheumatology and musculoskeletal disorders that affect the joints and connective tissue. Each bimonthly issue includes articles giving you the latest diagnostic criteria, consensus statements, systematic reviews and meta-analyses as well as clinical and translational research studies. Read this journal for the latest groundbreaking research and to gain insights from scientists and clinicians on the management and treatment of musculoskeletal and autoimmune rheumatologic diseases. The journal is of interest to rheumatologists, orthopedic surgeons, internal medicine physicians, immunologists and specialists in bone and mineral metabolism.
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