Smoking and Type 1 Versus Type 2 Myocardial Infarction Among People With HIV in the United States.

IF 1.6 4区医学 Q2 NURSING

Janac-Journal of the Association of Nurses in Aids Care Pub Date : 2024-09-06 DOI:10.1097/JNC.0000000000000492

Heidi M Crane, Robin M Nance, Stephanie A Ruderman, Lydia N Drumright, L Sarah Mixson, Susan R Heckbert, Matthew J Feinstein, Matthew J Budoff, Laura Bamford, Edward Cachay, Sonia Napravnik, Richard D Moore, Jeanne Keruly, Amanda L Willig, Greer A Burkholder, Andrew Hahn, Jimmy Ma, Rob Fredericksen, Michael S Saag, Geetanjali Chander, Mari M Kitahata, Kristina Crothers, Kenneth H Mayer, Conall O'Cleirigh, Karen Cropsey, Bridget M Whitney, Joseph A C Delaney

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引用次数: 0

Abstract

Abstract: Smoking is a myocardial infarction (MI) risk factor among people with HIV (PWH). Questions persist regarding the role of smoking behaviors and measurements (e.g., intensity, duration) on MI risk. We used Cox proportional hazards regression to compare the association of smoking parameterization with incidents of type 1 and type 2 MI and whether smoking intensity or duration improves MI risk prediction among PWH. Among 11,637 PWH, 37% reported currently smoking, and there were 346 MIs. Current smoking was associated with type 1 (84% increased risk) but not type 2 MI in adjusted analyses. The type 1 MI model with pack years had the best goodness of fit compared with other smoking parameterizations. Ever or never parameterization and smoking diagnosis data had significantly poorer model fit. These results highlight the importance of differentiating MI types and performing patient-based smoking assessments to improve HIV care and research rather than relying on smoking status from diagnoses.

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美国艾滋病病毒感染者中吸烟与 1 型和 2 型心肌梗死的关系。

摘要：吸烟是艾滋病病毒感染者（PWH）心肌梗死（MI）的危险因素之一。关于吸烟行为和测量方法（如强度、持续时间）对心肌梗死风险的作用，一直存在疑问。我们使用 Cox 比例危险回归法比较了吸烟参数与 1 型和 2 型心肌梗死发病率的关系，以及吸烟强度或持续时间是否能改善对艾滋病感染者心肌梗死风险的预测。在 11637 名威尔士人中，37% 的人表示目前正在吸烟，共发生了 346 例心肌梗死。在调整分析中，当前吸烟与 1 型心肌梗死（风险增加 84%）有关，但与 2 型心肌梗死无关。与其他吸烟参数化方法相比，1型心肌梗死模型的包年拟合度最高。曾经或从不参数化以及吸烟诊断数据的模型拟合度明显较差。这些结果凸显了区分MI类型和进行基于患者的吸烟评估对改善艾滋病护理和研究的重要性，而不是依赖于诊断中的吸烟状况。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Janac-Journal of the Association of Nurses in Aids Care 医学-护理

CiteScore

2.90

自引率

10.00%

发文量

120

期刊介绍： The Journal of the Association of Nurses in AIDS Care (JANAC) is a peer-reviewed, international nursing journal that covers the full spectrum of the global HIV epidemic, focusing on prevention, evidence-based care management, interprofessional clinical care, research, advocacy, policy, education, social determinants of health, epidemiology, and program development. JANAC functions according to the highest standards of ethical publishing practices and offers innovative publication options, including Open Access and prepublication article posting, where the journal can post articles before they are published with an issue.