Donanemab: First Approval.

IF 13 1区医学 Q1 PHARMACOLOGY & PHARMACY

Drugs Pub Date : 2024-09-06 DOI:10.1007/s40265-024-02087-4

Connie Kang

引用次数: 0

Abstract

Donanemab (donanemab-azbt; Kisunla^TM) is an amyloid β-directed antibody developed by Eli Lilly and Company for the treatment of Alzheimer's disease. Donanemab recently received approval in the USA for the treatment of adults with early symptomatic Alzheimer's disease (patients with mild cognitive impairment or mild dementia stage of disease). This article summarizes the milestones in the development of donanemab leading to this first approval for Alzheimer's disease.

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多奈单抗：首次批准。

多奈单抗（donanemab-azbt；KisunlaTM）是礼来公司开发的一种淀粉样β定向抗体，用于治疗阿尔茨海默病。多奈单抗最近在美国获得批准，用于治疗有早期症状的阿尔茨海默病成人患者（轻度认知障碍或轻度痴呆阶段的患者）。本文总结了多那尼单抗开发过程中的里程碑事件，这些事件促成了多那尼单抗首次获批用于阿尔茨海默病的治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Drugs 医学-毒理学

CiteScore

22.70

自引率

0.90%

发文量

134

审稿时长

3-8 weeks

期刊介绍： Drugs is a journal that aims to enhance pharmacotherapy by publishing review and original research articles on key aspects of clinical pharmacology and therapeutics. The journal includes: Leading/current opinion articles providing an overview of contentious or emerging issues. Definitive reviews of drugs and drug classes, and their place in disease management. Therapy in Practice articles including recommendations for specific clinical situations. High-quality, well designed, original clinical research. Adis Drug Evaluations reviewing the properties and place in therapy of both newer and established drugs. AdisInsight Reports summarising development at first global approval. Moreover, the journal offers additional digital features such as animated abstracts, video abstracts, instructional videos, and podcasts to increase visibility and educational value. Plain language summaries accompany articles to assist readers with some knowledge of the field in understanding important medical advances.

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