Heterochromatin: Hiding from the remodeling machines

IF 14.5 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecular Cell Pub Date : 2024-09-05 DOI:10.1016/j.molcel.2024.08.012

Craig L. Peterson

引用次数: 0

Abstract

In this issue of Molecular Cell, Sahu et al.¹ find that shielding heterochromatin from SWI/SNF chromatin remodelers is essential to maintain and epigenetically propagate pre-existing heterochromatin domains, whereas SWI/SNF action protects facultative heterochromatic regions from premature silencing.

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异染色质：躲避重塑机器的攻击

在本期的《分子细胞》（Molecular Cell）杂志上，Sahu 等人1 发现，保护异染色质不受 SWI/SNF 染色质重塑者的影响，对于维持和表观遗传学上传播先前存在的异染色质结构域至关重要，而 SWI/SNF 的作用则能保护变性异染色质区域免于过早沉默。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecular Cell 生物-生化与分子生物学

CiteScore

26.00

自引率

3.80%

发文量

389

审稿时长

1 months

期刊介绍： Molecular Cell is a companion to Cell, the leading journal of biology and the highest-impact journal in the world. Launched in December 1997 and published monthly. Molecular Cell is dedicated to publishing cutting-edge research in molecular biology, focusing on fundamental cellular processes. The journal encompasses a wide range of topics, including DNA replication, recombination, and repair; Chromatin biology and genome organization; Transcription; RNA processing and decay; Non-coding RNA function; Translation; Protein folding, modification, and quality control; Signal transduction pathways; Cell cycle and checkpoints; Cell death; Autophagy; Metabolism.