Preoperative protective stenting of the carotid artery in severe complex head and neck cancer resection

IF 5.4 3区材料科学 Q2 CHEMISTRY, PHYSICAL

ACS Applied Energy Materials Pub Date : 2024-09-04 DOI:10.1016/j.oraloncology.2024.107012

Ji Xiaoyu , Pan Baihong , Li Yaozhen, Chen Shen, Sheng Chang, Liu Tinghua, Ouyang Yang

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引用次数: 0

Abstract

Objective

To investigate effects of preoperative protective carotid artery (CA) stenting in complex head and neck cancer (HNC) resection.

Material and methods

HNC that encases the CA is complex. Fifty-five patients diagnosed with complex HNC from 2018 to 2021 were enrolled, and were divided into Control group (general complex cases) and carotid artery stent (CAS) group (severe complex cases). All patients underwent standard tumor resection, while patients in the CAS group also underwent preoperative covered CA stenting. Medical information was retrospectively analyzed.

Results

CA stenting and tumor resection were successfully performed. Baseline demographics were recorded. CAS and Control groups had similar results for complete tumor resection rate, operation time, and intraoperative blood loss, although the CA was obviously more involved in CAS group than in Control group. However, recurrence rate in the CAS group was significantly lower than Control group, indicating that preoperative CA stent implantation facilitates complete tumor removal. Furthermore, perioperative CA-associated complications including common/internal CA ligation were more frequent in Control group. Overall survival and disease-free survival rate in CAS group and Control group was 87.5% and 69.2%, respectively. Disease-free survival rate in CAS group and Control group was 87.5% and 42.3%, respectively. No postoperative cerebral infarction was observed in either group. Overall hospitalization cost was recorded.

Conclusions

Preoperative protective CA stenting facilitates more thorough tumor removal while better preserving the CA during complex HNC resection, reducing the surgical difficulty. Preoperative CA stenting may be a safe and effective therapeutic option for resection of HNC encasing the CA.

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严重复杂头颈癌切除术中的颈动脉术前保护性支架植入术

摘要] 目的探讨术前保护性颈动脉（CA）支架植入术在复杂头颈部肿瘤（HNC）切除术中的应用效果。入选2018年至2021年确诊的55例复杂HNC患者，分为对照组（一般复杂病例）和颈动脉支架（CAS）组（严重复杂病例）。所有患者均接受了标准肿瘤切除术，而CAS组患者也在术前接受了覆盖CA支架植入术。结果成功实施了CA支架植入术和肿瘤切除术。记录了基线人口统计学特征。CAS组和对照组在肿瘤完全切除率、手术时间和术中失血量方面结果相似，但CAS组的CA受累程度明显高于对照组。然而，CAS组的复发率明显低于对照组，这表明术前植入CA支架有利于肿瘤的完全切除。此外，CA相关的围手术期并发症（包括CA总/内结扎）在对照组中更为常见。CAS组和对照组的总生存率和无病生存率分别为87.5%和69.2%。CAS组和对照组的无病生存率分别为87.5%和42.3%。两组均未观察到术后脑梗塞。结论术前保护性CA支架植入术有助于更彻底地切除肿瘤，同时在复杂的HNC切除术中更好地保留CA，降低手术难度。术前CA支架植入可能是切除包裹CA的HNC的一种安全有效的治疗方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Energy Materials Materials Science-Materials Chemistry

CiteScore

10.30

自引率

6.20%

发文量

1368

期刊介绍： ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.