Anterior Cruciate Ligament Reconstruction in Patients Aged 50 Years and Older Results in Improvements in Activity and Functional Outcome Measures, Whereas Reported Complication Rates Vary Widely: A Systematic Review.

IF 4.4 1区 医学 Q1 ORTHOPEDICS
Rodrigo Saad Berreta, Derrick M Knapik, Jad Lawand, Logan Moews, Juan Bernardo Villarreal-Espinosa, Lucas Pallone, Udit Dave, Jonathan Spaan, José Rafael Garcia, Salvador Ayala, Nikhil N Verma, Jorge Chahla
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Abstract

Purpose: To systematically review the contemporary literature and evaluate patient-reported outcome measures (PROMs), functional knee measures, and the incidence of complications in patients aged 50 years and older undergoing anterior cruciate ligament reconstruction (ACLR) at short- to mid-term follow-up.

Methods: A literature search was conducted across the PubMed, Embase, and Scopus databases, spanning from database inception to November 2023, in accordance with the 2020 Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. The inclusion criteria consisted of clinical studies reporting PROMs, measures of knee stability, and complication rates after ACLR in patients aged 50 years and older with minimum 2-year follow-up. The Methodological Index for Non-randomized Studies criteria were used to assess study quality. Primary outcome measures consisted of changes in PROMs and complication rates after ACLR.

Results: A total of 17 studies, consisting of 1,163 patients undergoing ACLR, were identified. Autografts were used in 90.3% of patients, whereas 9.7% of patients were treated using allografts. At minimum 24-month follow-up, mean International Knee Documentation Committee scores ranged from 67.4 to 92.96; mean Lysholm scores, from 84.4 to 94.8; and mean Tegner scores, from 0.3 to 5.4. The mean side-to-side difference at final follow-up ranged from 1.2 to 2.4 mm, and the rates of recurrent instability ranged from 0% to 18%. Complication and revision rates ranged from 0% to 40.4% and 0% to 37.5%, respectively, with the highest rates observed in studies noting a high incidence of intraoperative cartilage lesions.

Conclusions: ACLR in patients aged 50 years and older results in favorable International Knee Documentation Committee scores, Lysholm scores, and Tegner activity scores and improvements in functional knee measures. However, a wide range of reoperations and complications are reported, attributed to varying levels of chondral injury and osteoarthritis, which warrant consideration when discussing expectations in patients aged 50 years and older undergoing ACLR.

Level of evidence: Level IV, systematic review of Level II to IV studies.

前交叉韧带重建术对 50 岁以上患者的功能结果和并发症发生率均有改善:系统回顾
目的:评估接受前交叉韧带重建术(ACLR)的 50 岁及以上患者的患者报告结果指标(PROMs)、膝关节功能指标和并发症发生率:根据 2020 年《系统综述和荟萃分析首选报告项目》(Preferred Reporting Items for Systematic Reviews and Meta-Analysis,PRISMA)指南,在 PubMed、Embase 和 Scopus 数据库中进行了文献检索,时间跨度从开始到 2023 年 11 月。纳入标准包括报告前交叉韧带置换术后 PROMs、膝关节稳定性测量和并发症发生率的临床研究,患者年龄≥ 50 岁,随访时间至少 2 年。采用非随机研究方法指数(MINORS)标准评估研究质量。主要结果指标包括前交叉韧带置换术后的PROMs变化和并发症发生率:共确定了 17 项研究,包括 1,163 名接受前交叉韧带置换术的患者。90.3%的患者使用了自体移植物,而9.7%的患者使用了异体移植物。在最短24个月的随访中,平均国际膝关节文献评分(IKDC)从67.4分到92.96分不等,平均Lysholm评分从84.4分到94.8分不等,平均Tegner评分从0.3分到5.4分不等。最终随访时的平均侧对侧差异为1.2至2.4毫米,而复发性不稳定的发生率为0至18%。并发症和翻修率分别为0%至40.4%和0%至37.5%,其中术中软骨损伤发生率较高的研究观察到的并发症和翻修率最高:结论:对50岁以上的患者进行前交叉韧带重建可获得良好的IKDC、Lysholm和Tegner活动评分,并改善膝关节功能。然而,有报道称,由于软骨损伤和骨关节炎的程度不同,再手术和并发症的范围很广,因此在讨论 50 岁及以上接受前交叉韧带重建术的患者的期望时应加以考虑:IV,II-IV级研究的系统性回顾。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
9.30
自引率
17.00%
发文量
555
审稿时长
58 days
期刊介绍: Nowhere is minimally invasive surgery explained better than in Arthroscopy, the leading peer-reviewed journal in the field. Every issue enables you to put into perspective the usefulness of the various emerging arthroscopic techniques. The advantages and disadvantages of these methods -- along with their applications in various situations -- are discussed in relation to their efficiency, efficacy and cost benefit. As a special incentive, paid subscribers also receive access to the journal expanded website.
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