Hernando Cifuentes-Lobelo, Marcelo A Castañeda-Duarte, Diego Ruiz-Diaz, William Cortes-Lozano
{"title":"Ectopic Intrasphenoidal Growth Hormone Releasing Pituitary Adenoma Associated with an Intracranial Aneurysm.","authors":"Hernando Cifuentes-Lobelo, Marcelo A Castañeda-Duarte, Diego Ruiz-Diaz, William Cortes-Lozano","doi":"10.1055/s-0042-1757434","DOIUrl":null,"url":null,"abstract":"<p><p>Pituitary adenomas are a type of of the most frequent intracranial tumors. These tumors can extend outside the sella, but very rarely originate ectopically to the sellar region. A 71-year-old patient presented to our institution, with prior clinical history of noncontrolled arterial hypertension and new-onset high-intensity pulsatile headache. Upon suspicion of a hypertensive emergency with probable brain compromise, a nonenhanced computed tomography of the head was performed. A mass within the sphenoid sinus was found. Endocrinological workup demonstrated a significant elevation of the growth hormone. As an incidental finding, a brain aneurysm was evidenced, which was treated endovascularly prior to the mass treatment. Subsequently, the patient successfully underwent a gross total resection through an endonasal transsphenoidal approach. Histopathological results were consistent with a pituitary ectopic adenoma. A postoperative improvement in levels of somatomedin C was documented postoperatively.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 3","pages":"520-525"},"PeriodicalIF":0.0000,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11349417/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian journal of neurosurgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/s-0042-1757434","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Pituitary adenomas are a type of of the most frequent intracranial tumors. These tumors can extend outside the sella, but very rarely originate ectopically to the sellar region. A 71-year-old patient presented to our institution, with prior clinical history of noncontrolled arterial hypertension and new-onset high-intensity pulsatile headache. Upon suspicion of a hypertensive emergency with probable brain compromise, a nonenhanced computed tomography of the head was performed. A mass within the sphenoid sinus was found. Endocrinological workup demonstrated a significant elevation of the growth hormone. As an incidental finding, a brain aneurysm was evidenced, which was treated endovascularly prior to the mass treatment. Subsequently, the patient successfully underwent a gross total resection through an endonasal transsphenoidal approach. Histopathological results were consistent with a pituitary ectopic adenoma. A postoperative improvement in levels of somatomedin C was documented postoperatively.
垂体腺瘤是一种最常见的颅内肿瘤。这些肿瘤可延伸至蝶鞍外,但极少异位起源于蝶鞍区。一名 71 岁的患者来我院就诊,既往有未控制的动脉高血压临床病史,并伴有新发的高强度搏动性头痛。由于怀疑是高血压急症并可能危及脑部,医生为其进行了头部非增强计算机断层扫描。发现蝶窦内有肿块。内分泌检查显示生长激素显著升高。偶然发现了脑动脉瘤,在肿块治疗前进行了血管内治疗。随后,患者成功地通过鼻内镜经蝶窦途径进行了全切除术。组织病理学结果与垂体异位腺瘤一致。术后记录显示,患者体内的体液调节素 C 水平有所改善。