Prevalence of low vitamin D levels among older US Asian and Pacific Islander adults.

IF 4.2 2区医学 Q1 ENDOCRINOLOGY & METABOLISM

Osteoporosis International Pub Date : 2024-11-01 Epub Date: 2024-08-29 DOI:10.1007/s00198-024-07197-z

Wei Yang, Malini Chandra, Nancy P Gordon, Jeanne A Darbinian, Julia C Drees, Jennifer Park-Sigal, Catherine Lee, Joan C Lo

{"title":"Prevalence of low vitamin D levels among older US Asian and Pacific Islander adults.","authors":"Wei Yang, Malini Chandra, Nancy P Gordon, Jeanne A Darbinian, Julia C Drees, Jennifer Park-Sigal, Catherine Lee, Joan C Lo","doi":"10.1007/s00198-024-07197-z","DOIUrl":null,"url":null,"abstract":"While US Asian and Pacific Islander adults have lower 25-hydroxyvitamin D (25(OH)D) levels than White adults, ethnic subgroup data remain limited. In a large California population, the adjusted prevalence of 25(OH)D < 20 ng/mL (50 nmol/L) was 1.5- to 2.7-fold higher for Asian/Pacific Islander compared to White adults, with substantial variation by ethnicity.Purpose: US Asian and Pacific Islander (PI) adults generally have lower 25-hydroxyvitamin D [25(OH)D] levels than non-Hispanic White (NHW) adults, but subgroup data remain limited. We compared sex- and ethnicity-specific prevalence of low 25(OH)D among older Asian/PI and NHW adults.Methods: Data from 102,556 Asian/PI and 381,724 NHW adults aged 50-89 years with measured 25(OH)D in 2012-2019 and body mass index (BMI, within ± 1 year) were examined in a California healthcare system. Low 25(OH)D < 20 ng/mL (50 nmol/L) was examined by race and ethnicity. Covariates included age, smoking, BMI, and season of measurement. Modified Poisson regression was used to estimate prevalence ratios (aPR), adjusting for covariates.Results: Among 31,287 Asian/PI men and 71,269 Asian/PI women, the prevalence of low 25(OH)D was 22.6% and 14.7%, respectively, significantly higher than observed for 122,162 NHW men (12.3%) and 259,562 NHW women (9.9%). Within Asian/PI subgroups, low 25(OH)D prevalence ranged from 17 to 18% (Korean, Japanese, Filipino), 22 to 24% (Chinese, Vietnamese), 28% (South Asian), and 35% (Native Hawaiian/PI) among men and 11 to 14% (Japanese, Filipina, Chinese, Korean), 17 to 18% (South Asian, Vietnamese), and 26% (Native Hawaiian/PI) among women. The corresponding aPRs (NHW reference) for men and women were as follows: Native Hawaiian/PI, 2.70 and 2.34; South Asian, 2.56 and 2.07; Vietnamese, 2.17 and 2.31; Chinese, 2.04 and 1.89; Korean, 1.60 and 1.85; Filipino, 1.58 and 1.52; and Japanese, 1.58 and 1.49 (p < 0.001).Conclusion: In a large US healthcare population of older Asian/PI adults, low 25(OH)D prevalence was 1.5- to 2.7-fold higher for Asian/PI compared to NHW adults, with substantial variation by sex and ethnicity.","PeriodicalId":19638,"journal":{"name":"Osteoporosis International","volume":null,"pages":null},"PeriodicalIF":4.2000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Osteoporosis International","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00198-024-07197-z","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/8/29 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}

引用次数: 0

Abstract

While US Asian and Pacific Islander adults have lower 25-hydroxyvitamin D (25(OH)D) levels than White adults, ethnic subgroup data remain limited. In a large California population, the adjusted prevalence of 25(OH)D < 20 ng/mL (50 nmol/L) was 1.5- to 2.7-fold higher for Asian/Pacific Islander compared to White adults, with substantial variation by ethnicity.

Purpose: US Asian and Pacific Islander (PI) adults generally have lower 25-hydroxyvitamin D [25(OH)D] levels than non-Hispanic White (NHW) adults, but subgroup data remain limited. We compared sex- and ethnicity-specific prevalence of low 25(OH)D among older Asian/PI and NHW adults.

Methods: Data from 102,556 Asian/PI and 381,724 NHW adults aged 50-89 years with measured 25(OH)D in 2012-2019 and body mass index (BMI, within ± 1 year) were examined in a California healthcare system. Low 25(OH)D < 20 ng/mL (50 nmol/L) was examined by race and ethnicity. Covariates included age, smoking, BMI, and season of measurement. Modified Poisson regression was used to estimate prevalence ratios (aPR), adjusting for covariates.

Results: Among 31,287 Asian/PI men and 71,269 Asian/PI women, the prevalence of low 25(OH)D was 22.6% and 14.7%, respectively, significantly higher than observed for 122,162 NHW men (12.3%) and 259,562 NHW women (9.9%). Within Asian/PI subgroups, low 25(OH)D prevalence ranged from 17 to 18% (Korean, Japanese, Filipino), 22 to 24% (Chinese, Vietnamese), 28% (South Asian), and 35% (Native Hawaiian/PI) among men and 11 to 14% (Japanese, Filipina, Chinese, Korean), 17 to 18% (South Asian, Vietnamese), and 26% (Native Hawaiian/PI) among women. The corresponding aPRs (NHW reference) for men and women were as follows: Native Hawaiian/PI, 2.70 and 2.34; South Asian, 2.56 and 2.07; Vietnamese, 2.17 and 2.31; Chinese, 2.04 and 1.89; Korean, 1.60 and 1.85; Filipino, 1.58 and 1.52; and Japanese, 1.58 and 1.49 (p < 0.001).

Conclusion: In a large US healthcare population of older Asian/PI adults, low 25(OH)D prevalence was 1.5- to 2.7-fold higher for Asian/PI compared to NHW adults, with substantial variation by sex and ethnicity.

Abstract Image

查看原文本刊更多论文

美国亚裔和太平洋岛民中老年人维生素 D 含量低的患病率。

尽管美国亚裔和太平洋岛民成年人的 25- 羟基维生素 D（25(OH)D）水平低于白人成年人，但种族亚群数据仍然有限。在加利福尼亚州的一个大型人群中，25（OH）D 的调整患病率目的：美国亚裔和太平洋岛民（PI）成年人的 25- 羟维生素 D [25(OH)D] 水平普遍低于非西班牙裔白人（NHW）成年人，但亚组数据仍然有限。我们比较了亚裔/白种人和非西班牙裔白种人中25（OH）D偏低的性别和种族患病率：我们研究了加利福尼亚州医疗保健系统中 102,556 名亚裔/PI 和 381,724 名 50-89 岁 NHW 成年人的数据，他们在 2012-2019 年测量了 25(OH)D 和体重指数（BMI，± 1 年内）。低 25(OH)D 结果：在 31,287 名亚裔/菲律宾裔男性和 71,269 名亚裔/菲律宾裔女性中，25（OH）D 偏低的发生率分别为 22.6% 和 14.7%，明显高于在 122,162 名非正常体重男性（12.3%）和 259,562 名非正常体重女性（9.9%）中观察到的结果。在亚洲/太平洋岛屿族裔亚群中，男性 25(OH)D 低流行率为 17%至 18%（韩国人、日本人、菲律宾人）、22%至 24%（中国人、越南人）、28%（南亚人）和 35%（夏威夷原住民/太平洋岛屿族裔），女性为 11%至 14%（日本人、菲律宾人、中国人、韩国人）、17%至 18%（南亚人、越南人）和 26%（夏威夷原住民/太平洋岛屿族裔）。男性和女性的相应 aPRs（NHW 参考值）如下：夏威夷原住民/印地安人，2.70 和 2.34；南亚人，2.56 和 2.07；越南人，2.17 和 2.31；中国人，2.04 和 1.89；韩国人，1.60 和 1.85；菲律宾人，1.58 和 1.52；日本人，1.58 和 1.49（P 结论：在美国大量的医疗保健人群中，男性和女性的 aPRs（NHW 参考值）分别为 2.70 和 2.34，2.56 和 2.07，2.17 和 2.31：在美国庞大的亚裔/太平洋岛屿族裔老年人医疗保健人群中，亚裔/太平洋岛屿族裔的 25（OH）D 低患病率是白血病患病率的 1.5 至 2.7 倍，不同性别和族裔的患病率差异很大。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Osteoporosis International 医学-内分泌学与代谢

CiteScore

8.10

自引率

10.00%

发文量

224

审稿时长

3 months

期刊介绍： An international multi-disciplinary journal which is a joint initiative between the International Osteoporosis Foundation and the National Osteoporosis Foundation of the USA, Osteoporosis International provides a forum for the communication and exchange of current ideas concerning the diagnosis, prevention, treatment and management of osteoporosis and other metabolic bone diseases. It publishes: original papers - reporting progress and results in all areas of osteoporosis and its related fields; review articles - reflecting the present state of knowledge in special areas of summarizing limited themes in which discussion has led to clearly defined conclusions; educational articles - giving information on the progress of a topic of particular interest; case reports - of uncommon or interesting presentations of the condition. While focusing on clinical research, the Journal will also accept submissions on more basic aspects of research, where they are considered by the editors to be relevant to the human disease spectrum.