The effect of human assumed central sensitization on transforaminal epidural steroid injection in chronic lumbar radiculopathy: An observational study.

IF 1.4 4区 医学 Q3 ORTHOPEDICS
Tülay Sahin, Rekib Sacaklidir, Mert Sancar, Ekim Can Öztürk
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引用次数: 0

Abstract

Background: Human assumed central sensitization (HACS) is a potential pathophysiological mechanism underlying a group of musculoskeletal disorders. HACS may negatively influence the outcomes of surgical or interventional procedures.

Objective: The present study aimed to investigate the impact of HACS on treatment outcomes of transforaminal epidural steroid injection (TFESI).

Methods: Patients who received fluoroscopy-guided single-level lumbosacral TFESI between January 2020 and January 2021 were included in the study. The patients were divided into two groups with respect to the existence of HACS. Patients were assessed before the procedure, at the third week, and at the third month after the procedure. The presence of HACS was investigated by central sensitization inventory (CSI). The Numerical Rating Scale (NRS), Oswestry Disability Index (ODI), and Beck Depression Inventory (BDI) were used for patient assessment.

Results: A total of 65 patients were included in the study. Thirty-one of the patients had HACS. There was no difference between the groups in terms of demographic data. Significant improvement in NRS was found at 3rd week and 3rd month compared to the baseline. BDI and ODI scores were also significantly reduced at the end of 3 months (p< 0.001). NRS scores at all time points were significantly lower in patients without HACS (p< 0.05).

Conclusion: The presence of HACS has a negative effect on pain scores, disability, and mental state in patients undergoing TFESI.

经椎间孔硬膜外注射类固醇对慢性腰椎病的影响:一项观察性研究。
背景:人体假定中枢过敏(HACS)是一组肌肉骨骼疾病的潜在病理生理机制。HACS 可能会对手术或介入治疗的结果产生负面影响:本研究旨在探讨 HACS 对经穿孔硬膜外类固醇注射(TFESI)治疗效果的影响:研究纳入了 2020 年 1 月至 2021 年 1 月期间接受透视引导下单层腰骶部 TFESI 的患者。根据是否存在 HACS 将患者分为两组。分别在手术前、手术后第三周和手术后第三个月对患者进行评估。HACS的存在情况通过中枢敏感性量表(CSI)进行调查。数字评定量表(NRS)、奥斯韦斯特里残疾指数(ODI)和贝克抑郁量表(BDI)用于患者评估:研究共纳入 65 名患者。结果:研究共纳入 65 名患者,其中 31 名患者患有 HACS。两组患者在人口统计学数据方面没有差异。与基线相比,第 3 周和第 3 个月的 NRS 有明显改善。3个月后,BDI和ODI评分也明显降低(P< 0.001)。没有 HACS 的患者在所有时间点的 NRS 评分都明显较低(p< 0.05):结论:HACS的存在对TFESI患者的疼痛评分、残疾程度和精神状态有负面影响。
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来源期刊
CiteScore
2.70
自引率
0.00%
发文量
194
审稿时长
6 months
期刊介绍: The Journal of Back and Musculoskeletal Rehabilitation is a journal whose main focus is to present relevant information about the interdisciplinary approach to musculoskeletal rehabilitation for clinicians who treat patients with back and musculoskeletal pain complaints. It will provide readers with both 1) a general fund of knowledge on the assessment and management of specific problems and 2) new information considered to be state-of-the-art in the field. The intended audience is multidisciplinary as well as multi-specialty. In each issue clinicians can find information which they can use in their patient setting the very next day.
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