Remote Ischemic Conditioning Improves Cardiovascular Function in Heart Failure Patients.

IF 1.4 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Cardiology Research Pub Date : 2024-08-01 Epub Date: 2024-07-18 DOI:10.14740/cr1669

Miin-Yaw Shyu, Andrew Ying-Siu Lee

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引用次数: 0

Abstract

Background: Recently, it has been shown that remote ischemic conditioning (RIC) can be used as a healthy regimen to reverse disease and aging. With this in mind, we are studying the consequences of RIC on cardiovascular function in heart failure patients.

Methods: Forty patients with stable heart failure were prospectively enlisted and randomly divided into RIC (n = 20) and control (n = 20) groups. The RIC protocol consists of a 3-min inflation and then deflation of the blood pressure cuff attached to the upper arm to produce transient ischemia of the arm. RIC treatment was performed once daily for 1 year. NYHA class, left ventricular ejection fraction (LVEF), left atrial and ventricular dimensions were all assessed in two groups.

Results: RIC was well tolerated. After 1 year of treatment, New York Heart Association (NYHA) class improved and LVEF showed a significant increase from 37.11% to 52.44% (P < 0.0001). Additionally, the dimensions of the left atrium (from 50.55 to 43.25 mm) and ventricle (from 53.04 to 50.15 mm) were significantly reduced in the RIC group.

Conclusion: This study suggests that 1 year of RIC treatment as a health strategy could improve cardiovascular function in heart failure patients, leading to its widespread use in these patients.

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远程缺血调节改善心衰患者的心血管功能

背景：最近有研究表明，远程缺血调理（RIC）可作为一种健康疗法来逆转疾病和衰老。有鉴于此，我们正在研究 RIC 对心衰患者心血管功能的影响：方法：我们对 40 名稳定型心衰患者进行了前瞻性招募，并将其随机分为 RIC 组（20 人）和对照组（20 人）。RIC 方案包括将连接在上臂的血压袖带充气 3 分钟，然后放气，以产生短暂的手臂缺血。RIC 治疗每天进行一次，持续 1 年。对两组患者的 NYHA 分级、左心室射血分数（LVEF）、左心房和左心室尺寸进行评估：结果：RIC 的耐受性良好。治疗一年后，纽约心脏协会（NYHA）分级得到改善，左心室射血分数（LVEF）从 37.11% 显著增加到 52.44%（P < 0.0001）。此外，RIC 组的左心房（从 50.55 毫米降至 43.25 毫米）和左心室（从 53.04 毫米降至 50.15 毫米）的尺寸也明显缩小：本研究表明，作为一种健康策略，RIC 治疗 1 年可改善心衰患者的心血管功能，因此可在这些患者中广泛使用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cardiology Research CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

2.50

自引率

0.00%

发文量

期刊介绍： Cardiology Research is an open access, peer-reviewed, international journal. All submissions relating to basic research and clinical practice of cardiology and cardiovascular medicine are in this journal''s scope. This journal focuses on publishing original research and observations in all cardiovascular medicine aspects. Manuscript types include original article, review, case report, short communication, book review, letter to the editor.