Disproportionate Racial Impact against Hepatic Cancer Patients: NIS 2020

IF 2.5 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Journal of the National Medical Association Pub Date : 2024-08-01 DOI:10.1016/j.jnma.2024.07.055

Narathorn Kulthamrongsri MD, Kanthajan Tatchaya MD, Kulthamrongsri Narathorn MD, Prasitsumrit Vitchapong MD

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引用次数: 0

Abstract

Introduction

Hepatobiliary cancer is the second leading cause of cancer-related death worldwide. Prior data showed mixed results against racial impact in this population group, with limited specific results regarding clinical outcomes. We aim to utilize a large national database to provide comprehensive data on the clinical outcomes of hepatobiliary cancer about race.

Method

The 2020 National Inpatient Sample was utilized in this study. patients with hepatobiliary cancer were selected by ICD-10 CM code. Inpatient mortality and associated complications, including acute kidney injury (AKI), heart failure, and mechanical ventilation use were analyzed. Logistic regression analysis was used to assess the association between race and complications.

Results

We surveyed 20,670 hospitalizations with hepatobiliary cancer. Caucasians accounted for 60.7%, whereas African Americans accounted for 12%. The mean age was 65.38 years, with 66% being male. African Americans had a significantly higher inpatient mortality rate (aOR 1.61, 95%CI (1.10, 2.35), p <0.005) as well as higher odds of acute kidney injury (aOR 1.22; 95%CI (1.10-1.35), p<0.005) compared to Caucasians. We found increased, but not statistically significant in other clinical outcomes compared to Caucasians.

Conclusion

African Americans are at a higher risk of experiencing worsening clinical outcomes and mortality rates. Future longitudinal studies could shed light on these long-term connections.

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对肝癌患者造成的不成比例的种族影响：NIS 2020

导言肝胆癌是全球癌症相关死亡的第二大原因。之前的数据显示，在这一人群中，种族影响的结果不一，有关临床结果的具体结果有限。本研究采用了 2020 年全国住院病人抽样调查，通过 ICD-10 CM 编码筛选出肝胆癌患者。分析了住院患者的死亡率和相关并发症，包括急性肾损伤（AKI）、心力衰竭和机械通气的使用。结果我们调查了 20,670 例肝胆癌住院患者。白种人占 60.7%，非裔美国人占 12%。平均年龄为 65.38 岁，66% 为男性。与白种人相比，非裔美国人的住院死亡率明显更高（aOR 1.61，95%CI (1.10，2.35)，p<0.005），急性肾损伤的几率也更高（aOR 1.22；95%CI (1.10-1.35)，p<0.005）。我们发现，与白种人相比，非裔美国人的其他临床结果也有所增加，但无统计学意义。未来的纵向研究可以揭示这些长期联系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the National Medical Association 医学-医学：内科

CiteScore

4.80

自引率

3.00%

发文量

139

审稿时长

98 days

期刊介绍： Journal of the National Medical Association, the official journal of the National Medical Association, is a peer-reviewed publication whose purpose is to address medical care disparities of persons of African descent. The Journal of the National Medical Association is focused on specialized clinical research activities related to the health problems of African Americans and other minority groups. Special emphasis is placed on the application of medical science to improve the healthcare of underserved populations both in the United States and abroad. The Journal has the following objectives: (1) to expand the base of original peer-reviewed literature and the quality of that research on the topic of minority health; (2) to provide greater dissemination of this research; (3) to offer appropriate and timely recognition of the significant contributions of physicians who serve these populations; and (4) to promote engagement by member and non-member physicians in the overall goals and objectives of the National Medical Association.