Ensifentrine: First Approval.

IF 13 1区医学 Q1 PHARMACOLOGY & PHARMACY

Drugs Pub Date : 2024-08-28 DOI:10.1007/s40265-024-02081-w

Susan J Keam

引用次数: 0

Abstract

Ensifentrine, an inhaled, selective phosphodiesterase (PDE) 3 and PDE4 inhibitor, is being developed by Verona Pharma plc for the treatment of respiratory diseases, including chronic obstructive pulmonary disease (COPD). In June 2024, ensifentrine (OHTUVAYRE™) inhalation suspension was approved for the maintenance treatment of COPD in adult patients in the USA. This article summarizes the milestones in the development of ensifentrine leading to this first approval for the maintenance treatment of COPD.

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安眠酮首次批准。

Ensifentrine 是一种吸入式、选择性磷酸二酯酶 (PDE) 3 和 PDE4 抑制剂，由 Verona Pharma plc 开发，用于治疗呼吸系统疾病，包括慢性阻塞性肺病 (COPD)。2024 年 6 月，ensifentrine（OHTUVAYRE™）吸入悬浮剂在美国获准用于慢性阻塞性肺病成年患者的维持治疗。本文总结了安塞芬净研发过程中的里程碑事件，这些事件促成了安塞芬净首次获批用于慢性阻塞性肺病的维持治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Drugs 医学-毒理学

CiteScore

22.70

自引率

0.90%

发文量

134

审稿时长

3-8 weeks

期刊介绍： Drugs is a journal that aims to enhance pharmacotherapy by publishing review and original research articles on key aspects of clinical pharmacology and therapeutics. The journal includes: Leading/current opinion articles providing an overview of contentious or emerging issues. Definitive reviews of drugs and drug classes, and their place in disease management. Therapy in Practice articles including recommendations for specific clinical situations. High-quality, well designed, original clinical research. Adis Drug Evaluations reviewing the properties and place in therapy of both newer and established drugs. AdisInsight Reports summarising development at first global approval. Moreover, the journal offers additional digital features such as animated abstracts, video abstracts, instructional videos, and podcasts to increase visibility and educational value. Plain language summaries accompany articles to assist readers with some knowledge of the field in understanding important medical advances.

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