Estimated Financial Savings From Clinical Studies at Oslo Myeloma Center in the Period 2015-2021.

IF 2.7 4区 医学 Q2 HEMATOLOGY
Clinical Lymphoma, Myeloma & Leukemia Pub Date : 2025-01-01 Epub Date: 2024-07-31 DOI:10.1016/j.clml.2024.07.015
Lars Henrik Dahl Hamnvik, Stella Eide-Olsen, Arne Fosseng, Fredrik Hellem Schjesvold
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引用次数: 0

Abstract

Background: The number of clinical studies in the Western world has been declining the last decade. Clinical studies offer valuable opportunities for cancer patients to access new treatments and serve as arenas for learning and competence development for health care workers. In addition to this, clinical studies can significantly contribute to financial savings for the health care system through the provision of drugs. The extent of these savings have not been evaluated before.

Materials and methods: We assessed the financial savings from drugs provided in clinical studies conducted at Oslo Myeloma Center between 2015 and 2021. Only drugs that had marketing license or another equivalent drug with marketing license were considered to estimate savings.

Results: A total of 314 patients across 24 different studies were given treatment with drugs possessing marketing license. Drugs approved for clinical use and reimbursed by the national health care system gave a financial saving of 20.3 million USD and was considered a direct saving. Drugs not approved for clinical use, but having equivalent approved alternatives yielded a financial saving of 4.7 million USD.

Conclusion: Clinical studies not only offer new opportunities for patients and advancements in medical treatment and knowledge but also contribute significantly to financial saving for the health care system through reduced drug expenses.

奥斯陆骨髓瘤中心 2015-2021 年期间临床研究节省的资金估算。
背景:过去十年中,西方国家的临床研究数量一直在下降。临床研究为癌症患者提供了获得新疗法的宝贵机会,也是医护人员学习和提高能力的舞台。除此之外,临床研究还能通过提供药物为医疗保健系统节省大量资金。这些节约的程度以前从未进行过评估:我们评估了奥斯陆骨髓瘤中心在 2015 年至 2021 年期间开展的临床研究通过提供药物所节省的资金。只有拥有上市许可的药物或拥有上市许可的其他同等药物才被视为估算节省费用的对象:在 24 项不同的研究中,共有 314 名患者接受了拥有上市许可的药物治疗。经批准用于临床并由国家医疗系统报销的药物节省了 2030 万美元,被视为直接节省。未获批准用于临床的药物,但有同等的获批替代品,可节省 470 万美元:临床研究不仅为患者提供了新的机会,推动了医学治疗和知识的进步,还通过减少药物支出为医疗保健系统节省了大量资金。
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来源期刊
CiteScore
2.70
自引率
3.70%
发文量
1606
审稿时长
26 days
期刊介绍: Clinical Lymphoma, Myeloma & Leukemia is a peer-reviewed monthly journal that publishes original articles describing various aspects of clinical and translational research of lymphoma, myeloma and leukemia. Clinical Lymphoma, Myeloma & Leukemia is devoted to articles on detection, diagnosis, prevention, and treatment of lymphoma, myeloma, leukemia and related disorders including macroglobulinemia, amyloidosis, and plasma-cell dyscrasias. The main emphasis is on recent scientific developments in all areas related to lymphoma, myeloma and leukemia. Specific areas of interest include clinical research and mechanistic approaches; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; and integration of various approaches.
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