Lauren N Kennedy, Tomas L Griebling, Colby P Souders
{"title":"Updates on the use of neuromodulation in geriatric patients.","authors":"Lauren N Kennedy, Tomas L Griebling, Colby P Souders","doi":"10.1097/MOU.0000000000001215","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>In light of the updated AUA/SUFU guidelines on the diagnosis and treatment of overactive bladder (OAB), increased utilization of advanced therapies is expected in the coming years. The primary aim of this review is to summarize existing outcome and safety data on the use of neuromodulation in geriatric patients, as well as highlight recent advances in neuromodulation that may be particularly advantageous in the geriatric population.</p><p><strong>Recent findings: </strong>There are mixed data demonstrating efficacy of sacral neuromodulation by decade of life, with older individuals most often demonstrating lower odds of progressing to stage 2 implantation. However, a large majority of patients still undergo stage 2 implantation with no significant increase in complications reported when compared to younger cohorts. Neuromodulation is broadening to have wider indications outside of OAB, which may be particularly beneficial in the elderly population (fecal incontinence, nonobstructive urinary retention, and constipation). Posterior tibial nerve stimulation remains a well tolerated and efficacious treatment for OAB, with new FDA-approved implantable devices joining the commercial market, which may expand access for elderly populations.</p><p><strong>Summary: </strong>The data are encouraging and support the use of neuromodulation in geriatric patients.</p>","PeriodicalId":11093,"journal":{"name":"Current Opinion in Urology","volume":" ","pages":"428-432"},"PeriodicalIF":2.1000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Urology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/MOU.0000000000001215","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/8/22 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose of review: In light of the updated AUA/SUFU guidelines on the diagnosis and treatment of overactive bladder (OAB), increased utilization of advanced therapies is expected in the coming years. The primary aim of this review is to summarize existing outcome and safety data on the use of neuromodulation in geriatric patients, as well as highlight recent advances in neuromodulation that may be particularly advantageous in the geriatric population.
Recent findings: There are mixed data demonstrating efficacy of sacral neuromodulation by decade of life, with older individuals most often demonstrating lower odds of progressing to stage 2 implantation. However, a large majority of patients still undergo stage 2 implantation with no significant increase in complications reported when compared to younger cohorts. Neuromodulation is broadening to have wider indications outside of OAB, which may be particularly beneficial in the elderly population (fecal incontinence, nonobstructive urinary retention, and constipation). Posterior tibial nerve stimulation remains a well tolerated and efficacious treatment for OAB, with new FDA-approved implantable devices joining the commercial market, which may expand access for elderly populations.
Summary: The data are encouraging and support the use of neuromodulation in geriatric patients.
综述目的:根据美国膀胱过度活动症协会(AUA)/膀胱过度活动症联盟(SUFU)更新的膀胱过度活动症(OAB)诊断和治疗指南,预计未来几年先进疗法的使用率将有所提高。本综述的主要目的是总结在老年患者中使用神经调节疗法的现有疗效和安全性数据,并重点介绍神经调节疗法的最新进展,这些进展可能对老年患者特别有利:最近的研究结果:不同年龄段的骶神经调控疗效数据不一,老年患者进展到第二阶段植入的几率通常较低。不过,大多数患者仍接受第二阶段植入手术,并发症与年轻患者相比没有明显增加。神经调控的适应症正在扩大,不仅限于尿失禁,对老年人群(大便失禁、非梗阻性尿潴留和便秘)尤其有益。胫后神经刺激仍然是一种耐受性良好、疗效显著的 OAB 治疗方法,新的 FDA 批准的植入式设备已进入商业市场,这可能会扩大老年人群的使用范围。
期刊介绍:
Current Opinion in Urology delivers a broad-based perspective on the most recent and most exciting developments in urology from across the world. Published bimonthly and featuring ten key topics – including focuses on prostate cancer, bladder cancer and minimally invasive urology – the journal’s renowned team of guest editors ensure a balanced, expert assessment of the recently published literature in each respective field with insightful editorials and on-the-mark invited reviews.