snoRNAs in making “snoman” ribosomes

IF 14.5 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecular Cell Pub Date : 2024-08-22 DOI:10.1016/j.molcel.2024.07.029

Adrianna Dabrowska, Davide Ruggero

引用次数: 0

Abstract

In a recent study in Cell, Cheng and Wang et al.¹ show that the small nucleolar RNA (snoRNA) SNORA13 has a non-canonical role in ribosome biogenesis and senescence by acting directly on RPL23 and regulating its assembly into the 60S ribosomal subunit.

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制造 "snooman "核糖体的 snoRNA

最近，Cheng 和 Wang 等人1 在《细胞》（Cell）杂志上发表的一项研究表明，小核仁 RNA（snoRNA）SNORA13 直接作用于 RPL23，并调节其组装成 60S 核糖体亚基，从而在核糖体生物发生和衰老过程中发挥非经典作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecular Cell 生物-生化与分子生物学

CiteScore

26.00

自引率

3.80%

发文量

389

审稿时长

1 months

期刊介绍： Molecular Cell is a companion to Cell, the leading journal of biology and the highest-impact journal in the world. Launched in December 1997 and published monthly. Molecular Cell is dedicated to publishing cutting-edge research in molecular biology, focusing on fundamental cellular processes. The journal encompasses a wide range of topics, including DNA replication, recombination, and repair; Chromatin biology and genome organization; Transcription; RNA processing and decay; Non-coding RNA function; Translation; Protein folding, modification, and quality control; Signal transduction pathways; Cell cycle and checkpoints; Cell death; Autophagy; Metabolism.