Probable vector of Crimean-Congo hemorrhagic fever virus; Hyalomma aegyptium: a systematic review and meta-analysis.

IF 1.7 Q3 INFECTIOUS DISEASES

GERMS Pub Date : 2024-03-31 eCollection Date: 2024-03-01 DOI:10.18683/germs.2024.1417

Hamid Sadeghi, Saeideh Gholamzadeh Khoei, Sara Shahsavari, Masoumeh Aslanimehr, Farhad Nikkhahi, Abouzar Babaei, Nematollah Gheibi, Behzad Bizhani

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引用次数: 0

Abstract

Introduction: Crimean-Congo hemorrhagic fever (CCHF) is the widest emerging severe viral tick-borne disease affecting humans. Crimean-Congo haemorrhagic fever virus (CCHFV) circulates by routine enzootic tick-vertebrate hosts-tick transmission cycles. We aimed to evaluate the molecular prevalence of CCHFV in ticks on a global scale.

Methods: A systematic procedure was used to perform this review and meta-analysis using PubMed, Google Scholar, and Web of Science databases from 1 January 2000 through 12 April 2023. Of the 2310 papers identified, 43 articles met the inclusion criteria for this study.

Results: The overall prevalence of CCHFV was 4.0% (95%CI: 2.7-6.0%) in ticks on the global scale, with heterogeneity (I²=96.387; p=0.0001). The genus Hyalomma was shown as the most frequent tick infected with CCHFV 5.4% (95%CI: 3.3-8.7%). We found that the pooled prevalence of CCHFV was higher in Hyalomma aegyptium 27.6% (95%CI: 22.7-33.2%). The pooled prevalence was higher in Asia 5.1% (95%CI: 3.3-7.7%), and Spain 21.0% (95%CI: 3.4-66.9). The locations with annual rainfall of 401-1000 mm 6.1% (95%CI: 2.6-13.5%) and latitude of 31-40° 6.0% (95%CI: 4.1-8.9%) were associated with the greatest pooled prevalence of CCHFV in ticks.

Conclusions: Surveillance of CCHFV in ticks will give a better comprehension for the future implementation of public health interventions. The question of whether Hyalomma aegyptium is a plausible or certain vector should be the subject of further investigation.

查看原文本刊更多论文

克里米亚-刚果出血热病毒的可能病媒；埃及鬣蜥：系统综述和荟萃分析。

导言：克里米亚-刚果出血热（CCHF）是影响人类最广泛的新出现的严重病毒性蜱媒疾病。克里米亚-刚果出血热病毒（CCHFV）通过蜱-无脊椎动物宿主-蜱的常规流行传播循环进行传播。我们的目的是在全球范围内评估蜱虫中克里米亚-刚果出血热病毒的分子流行率：我们采用了一种系统性程序，使用 PubMed、Google Scholar 和 Web of Science 数据库对 2000 年 1 月 1 日至 2023 年 4 月 12 日期间的文献进行了综述和荟萃分析。在确定的 2310 篇论文中，有 43 篇符合本研究的纳入标准：结果：CCHFV 在全球范围内的总体流行率为 4.0%（95%CI：2.7-6.0%），存在异质性（I2=96.387；P=0.0001）。结果显示，Hyalomma 属蜱虫感染 CCHFV 的频率最高，为 5.4% (95%CI: 3.3-8.7%)。我们发现，埃及蜱（Hyalomma aegyptium）的 CCHFV 聚合感染率较高，为 27.6% (95%CI: 22.7-33.2%)。亚洲和西班牙的总流行率分别为 5.1%（95%CI：3.3-7.7%）和 21.0%（95%CI：3.4-66.9）。年降雨量为 401-1000 毫米的地区为 6.1%（95%CI：2.6-13.5%），纬度为 31-40° 的地区为 6.0%（95%CI：4.1-8.9%），这些地区的蜱虫中 CCHFV 的总流行率最高：结论：监测蜱虫中的 CCHFV 将有助于更好地了解未来公共卫生干预措施的实施情况。埃及蜱（Hyalomma aegyptium）是否是一种可信或确定的病媒这一问题应成为进一步调查的主题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

GERMS INFECTIOUS DISEASES-

CiteScore

2.80

自引率

5.00%

发文量