A retrospective assessment of the effectiveness of pulsed radiofrequency ablation in the treatment of chronic pain caused by advanced knee osteoarthritis.

IF 1.6 Q2 ANESTHESIOLOGY
Anna Rękas-Dudziak, Krzysztof Brzeziński, Edyta Kotlińska-Hasiec, Wojciech Dąbrowski, Przemysław Matuła, Włodzimierz Płotek
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Abstract

Introduction: Patients suffering from severe chronic pain often have problems finding an appropriate combination of painkillers. We retrospectively evaluated the effectiveness and safety of pulsed radiofrequency ablation (pRFA) of the genicular nerves in 96 patients with knee osteoarthritis (KO). We hypothesized that age, sex, and body mass index (BMI) may influence the quality of the pRFA treatment.

Material and methods: A diagnostic blockade with total volume of 9 ml of 1% lidocaine (WZF, Poland) combined with 4 mg of dexamethasone with subsequent pRFA with a radio frequency of 300-500 kHz under ultrasound guidance was used during the procedure. The study participants were assessed during regular monthly visits until 12 months.

Results: The nerves' ultrasound identification was successful in 90.62% of the cases. According to the numeric rating scale (NRS), pain was reduced by 50% or more in 64.06% of the cases. The average pain relief period lasted just over 7 and a half months. There were no pRFA-related complications or side effects of the drugs used.

Conclusions: pRFA seems to be safe and effective for the treatment of chronic pain in KO. The outcome of the treatment may be related to the patient's age (block duration increased with patient age) and sex (in women, the therapeutic effect was more effectively prolonged) in our study group. There was also higher effectiveness of pRFA in high-BMI patients, which was close to statistical significance ( P = 0.053).

对脉冲射频消融治疗晚期膝关节骨性关节炎引起的慢性疼痛效果的回顾性评估。
简介患有严重慢性疼痛的患者往往难以找到合适的止痛药组合。我们对 96 名膝骨关节炎(KO)患者的膝神经脉冲射频消融术(pRFA)的有效性和安全性进行了回顾性评估。我们假设年龄、性别和体重指数(BMI)可能会影响脉冲射频消融治疗的质量:在手术过程中,使用总容量为 9 毫升的 1%利多卡因(WZF,波兰)和 4 毫克地塞米松进行诊断性阻滞,随后在超声波引导下使用 300-500 千赫的射频进行 pRFA。研究参与者每月定期接受评估,直至 12 个月:结果:90.62%的病例通过超声波成功识别了神经。根据数字评分量表(NRS),64.06%的病例疼痛减轻了50%或更多。疼痛缓解期平均超过 7 个半月。没有出现与 pRFA 相关的并发症或所用药物的副作用。在我们的研究小组中,治疗效果可能与患者的年龄(阻滞时间随患者年龄的增长而延长)和性别(女性的治疗效果更有效)有关。高体重指数患者的 pRFA 疗效也更高,接近统计学意义(P = 0.053)。
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来源期刊
CiteScore
3.00
自引率
5.90%
发文量
48
审稿时长
25 weeks
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