Clear cell meningioma of the filum terminale in a 44-year-old woman - case report.

IF 1.5 4区 医学 Q4 NEUROSCIENCES
Piotr Glinka, Michał Sobstyl, Albert Acewicz, Piotr Bojarski
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Abstract

Clear cell meningioma (CCM) is a rare subtype of meningioma, especially unusual as a neoplasm of the filum terminale. Clear cell meningioma seems to have a more aggressive nature and a higher risk of recurrence than WHO grade I meningiomas. A 44-year-old woman presented with lower back pain radiating to the left leg and mild weakness in the left leg. Magnetic resonance imaging (MRI) showed a well-demarcated, intradural lesion filling the spinal canal at the L3-S1 levels and compressing the cauda equina. The patient underwent laminectomy from L3 to S1. During the operation, the filum terminale was identified as a structure that was disappearing into the tumor. The filum terminale was cut and the tumor was totally removed in one piece. Pathological findings were indicative of the diagnosis of clear cell meningioma, CNS WHO G2. Postoperative magnetic resonance imaging at 6 months showed no residual mass. Total surgical excision of the CCM of the spinal cord should be chosen as the optimal treatment. In addition, radiological follow-up is equally important due to the high risk of recurrence. Our case is unusual in that the tumor's location was the filum terminale.

一名 44 岁女性的终丝透明细胞脑膜瘤--病例报告。
透明细胞脑膜瘤(CCM)是脑膜瘤的一种罕见亚型,作为终丝肿瘤尤为罕见。与世卫组织 I 级脑膜瘤相比,透明细胞脑膜瘤似乎更具侵袭性,复发风险也更高。一名 44 岁的妇女因下腰痛放射至左腿和左腿轻度无力而就诊。磁共振成像(MRI)显示,一个界限清晰的硬膜内病变充满了L3-S1水平的椎管,并压迫马尾。患者接受了从 L3 到 S1 的椎板切除术。在手术过程中,发现终丝结构正在消失在肿瘤中。手术中,患者被发现有一根丝状物消失在肿瘤中,于是切除了丝状物,肿瘤被完整地切除。病理结果显示诊断为透明细胞脑膜瘤,中枢神经系统 WHO G2。术后 6 个月的磁共振成像显示无残留肿块。脊髓透明细胞脑膜瘤的最佳治疗方法是手术全切。此外,由于复发风险高,放射学随访也同样重要。我们的病例与众不同,因为肿瘤位于终丝。
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来源期刊
Folia neuropathologica
Folia neuropathologica 医学-病理学
CiteScore
2.50
自引率
5.00%
发文量
38
审稿时长
>12 weeks
期刊介绍: Folia Neuropathologica is an official journal of the Mossakowski Medical Research Centre Polish Academy of Sciences and the Polish Association of Neuropathologists. The journal publishes original articles and reviews that deal with all aspects of clinical and experimental neuropathology and related fields of neuroscience research. The scope of journal includes surgical and experimental pathomorphology, ultrastructure, immunohistochemistry, biochemistry and molecular biology of the nervous tissue. Papers on surgical neuropathology and neuroimaging are also welcome. The reports in other fields relevant to the understanding of human neuropathology might be considered.
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