Five-year trend in secondary prevention medication prescription and risk factor control among patients with diabetes mellitus and cardiovascular diseases in Perak health clinics.

Q3 Nursing
Malaysian Family Physician Pub Date : 2024-07-31 eCollection Date: 2024-01-01 DOI:10.51866/oa.572
Jazlan Jamaluddin, Mohd Azzahi Mohamed-Kamel, Nor Shazatul Salwana Din, Mohamad Zikri Mohamad-Isa
{"title":"Five-year trend in secondary prevention medication prescription and risk factor control among patients with diabetes mellitus and cardiovascular diseases in Perak health clinics.","authors":"Jazlan Jamaluddin, Mohd Azzahi Mohamed-Kamel, Nor Shazatul Salwana Din, Mohamad Zikri Mohamad-Isa","doi":"10.51866/oa.572","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Prescription of secondary prevention medications (SPMs) and effective control of cardiovascular risk factors (RFs) are crucial to reduce the risk of recurrent cardiovascular events, particularly in high-risk individuals including those with diabetes mellitus (DM). This study aimed to analyse the trends in SPM prescription and identify the factors associated with RF control among patients with DM and cardiovascular diseases in Perak health clinics.</p><p><strong>Methods: </strong>Data of patients with ischaemic heart disease (IHD) and cerebrovascular diseases (CeVDs) audited from 2018 to 2022, excluding those lost to follow-up, were extracted from the National Diabetes Registry. Descriptive and trend analyses were conducted. Multivariable logistic regression was utilised to identify the factors associated with RF control.</p><p><strong>Results: </strong>Most patients (76.7%) were aged ≥60 years and were Malays (62.3%). The majority had IHD (60.8%) and CeVDs (54.7%) for ≥5 years. SPM prescription increased significantly over the past 5 years. However, blood pressure (BP) and lipid control remained static. Good BP control was associated with a DM duration of ≥10 years and poor control with Malay ethnicity and prescription of two or three antihypertensives. Good DM control was associated with an age of ≥60 years and age at DM diagnosis of ≥60 years and poor control with Malay and Indian ethnicities, DM duration of ≥10 years and prescription of two or three and more glucose-lowering drugs. Poor lipid control was associated only with Malay and Indian ethnicities.</p><p><strong>Conclusion: </strong>SPM prescription has increased over time, but the achievement of treatment targets, particularly for lipid control, has remained poor and unchanged. Statin use is not associated with lipid control. The accessibility and availability of alternative lipid-lowering drugs must be improved to enhance overall RF control, especially lipid control, in patients with DM and cardiovascular diseases.</p>","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11330545/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Malaysian Family Physician","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.51866/oa.572","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Nursing","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction: Prescription of secondary prevention medications (SPMs) and effective control of cardiovascular risk factors (RFs) are crucial to reduce the risk of recurrent cardiovascular events, particularly in high-risk individuals including those with diabetes mellitus (DM). This study aimed to analyse the trends in SPM prescription and identify the factors associated with RF control among patients with DM and cardiovascular diseases in Perak health clinics.

Methods: Data of patients with ischaemic heart disease (IHD) and cerebrovascular diseases (CeVDs) audited from 2018 to 2022, excluding those lost to follow-up, were extracted from the National Diabetes Registry. Descriptive and trend analyses were conducted. Multivariable logistic regression was utilised to identify the factors associated with RF control.

Results: Most patients (76.7%) were aged ≥60 years and were Malays (62.3%). The majority had IHD (60.8%) and CeVDs (54.7%) for ≥5 years. SPM prescription increased significantly over the past 5 years. However, blood pressure (BP) and lipid control remained static. Good BP control was associated with a DM duration of ≥10 years and poor control with Malay ethnicity and prescription of two or three antihypertensives. Good DM control was associated with an age of ≥60 years and age at DM diagnosis of ≥60 years and poor control with Malay and Indian ethnicities, DM duration of ≥10 years and prescription of two or three and more glucose-lowering drugs. Poor lipid control was associated only with Malay and Indian ethnicities.

Conclusion: SPM prescription has increased over time, but the achievement of treatment targets, particularly for lipid control, has remained poor and unchanged. Statin use is not associated with lipid control. The accessibility and availability of alternative lipid-lowering drugs must be improved to enhance overall RF control, especially lipid control, in patients with DM and cardiovascular diseases.

霹雳州医疗诊所糖尿病和心血管疾病患者二级预防药物处方和风险因素控制的五年趋势。
导言:开具二级预防药物(SPMs)处方和有效控制心血管风险因素(RFs)是降低心血管事件复发风险的关键,尤其是包括糖尿病(DM)患者在内的高危人群。本研究旨在分析霹雳州医疗诊所中糖尿病和心血管疾病患者的SPM处方趋势,并确定与RF控制相关的因素:从国家糖尿病登记处提取了2018年至2022年接受审计的缺血性心脏病(IHD)和脑血管疾病(CeVDs)患者的数据,不包括失去随访的患者。进行了描述性分析和趋势分析。利用多变量逻辑回归确定与射频控制相关的因素:大多数患者(76.7%)年龄≥60岁,马来人(62.3%)。大多数患者(60.8%)患有高血压(IHD)和心血管疾病(54.7%)≥5年。在过去 5 年中,SPM 的处方量明显增加。然而,血压(BP)和血脂控制却保持不变。血压控制良好与糖尿病病程≥10年有关,血压控制不佳与马来人种和服用两种或三种降压药有关。糖尿病控制良好与年龄≥60 岁和糖尿病确诊年龄≥60 岁有关,控制不佳与马来和印度种族、糖尿病病程≥10 年以及服用两种或三种以上降糖药有关。血脂控制不佳仅与马来族和印度族有关:结论:随着时间的推移,他汀类药物的处方量有所增加,但治疗目标的实现情况,尤其是血脂控制情况,仍然较差且没有变化。他汀类药物的使用与血脂控制无关。必须改善替代性降脂药物的可及性和可用性,以提高糖尿病和心血管疾病患者的总体射频控制,尤其是血脂控制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Malaysian Family Physician
Malaysian Family Physician Medicine-Family Practice
CiteScore
1.20
自引率
0.00%
发文量
41
审稿时长
24 weeks
期刊介绍: The Malaysian Family Physician is the official journal of the Academy of Family Physicians of Malaysia. It is published three times a year. Circulation: The journal is distributed free of charge to all members of the Academy of Family Physicians of Malaysia. Complimentary copies are also sent to other organizations that are members of the World Organization of Family Doctors (WONCA).
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信