What is the current state of the art in incorporating antimicrobial agents into conventional glass ionomer cement? A systematic review

Germano C. Dutra , Simone Kreve , Andréa C. Reis
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Abstract

Statement of problem

Conventional glass ionomer cement has limited action on biofilm. Thus, studies seek to incorporate different antimicrobial agents into GIC to provide antimicrobial activity.

Purpose

The purpose of this systematic review was to review the current state of research regarding different antimicrobial agents incorporated into conventional GIC.

Material and method

Searches were conducted in the SCOPUS, PubMed/Medline, EMBASE, Web of Science, and Google Scholar databases using the terms: glass ionomer cement; anti-microbial agent; anti-infective agents; antimicrobial; hydrochloride, chlorhexidine; microbicide; agents, anti-infective; antibacterial. The risk of bias was performed by adaptation of the Joanna Briggs Institute's assessment instrument for quasi-experimental studies.

Results

A total of 798 articles were found in the databases, of which 242 were duplicates. Fifty-nine papers were eligible to be read in full, and 51 were included in this systematic review.

Conclusion

Different antimicrobial agents are studied and incorporated into the GIC. However, based on the studies included in this systematic review, no fully effective agent was found that could maintain the prolonged antimicrobial effect without causing harm to the GIC or the body.

在传统玻璃离子聚合物水泥中加入抗菌剂的技术现状如何?系统回顾
问题陈述传统的玻璃离聚体水泥对生物膜的作用有限。因此,研究人员试图在 GIC 中加入不同的抗菌剂,以提供抗菌活性。目的本系统综述旨在回顾有关传统 GIC 中加入不同抗菌剂的研究现状。材料和方法在 SCOPUS、PubMed/Medline、EMBASE、Web of Science 和 Google Scholar 数据库中使用以下术语进行了搜索:玻璃离子水泥;抗微生物剂;抗感染剂;抗菌剂;盐酸,洗必泰;杀微生物剂;抗感染剂;抗菌剂。结果 在数据库中共找到 798 篇文章,其中 242 篇为重复文章。有 59 篇论文符合全文阅读条件,其中 51 篇被纳入本系统综述。然而,根据本系统综述所纳入的研究,没有发现一种完全有效的制剂可以在不对 GIC 或人体造成伤害的情况下保持长期的抗菌效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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