Development and Characterization of Silver Doped Hydroxyapatite/Chitosan Nanobiocomposites

Q3 Materials Science

Macromolecular Symposia Pub Date : 2024-08-16 DOI:10.1002/masy.202400023

Simona Liliana Iconaru, Steluta Carmen Ciobanu, Mihai-Valentin Predoi, Liliana Ghegoiu, Monica Luminita Badea, Roxana Trusca, Daniela Predoi, Gabriel Jiga

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引用次数: 0

Abstract

The aim of this study is to develop a new nanobiocomposite based on silver doped hydroxyapatite (AgHAp)/chitosan (CH), AgHAp-CH (x_Ag = 0.15) by an adapted method. The obtained nanobiocomposites are studied by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) studies. The good stability of AgHAp-CH suspension is established by ultrasound and zeta potential measurements. More than that, the antimicrobial activity of AgHAp-CH nanobiocomposites against Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, and Candida albicans ATCC 10231 microbial strains is evaluated. AgHAp-CH nanobiocomposites demonstrate an effective antibacterial effect against the studied microbial strains. Considering the facile method involved in the development of these nanobiomaterials and their excellent properties, it is suggested that they can be suitable candidates for applications in the biomedical field.

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掺银羟基磷灰石/壳聚糖纳米生物复合材料的开发与表征

本研究的目的是通过改良方法开发一种基于掺银羟基磷灰石（AgHAp）/壳聚糖（CH）的新型纳米生物复合材料，即 AgHAp-CH (xAg = 0.15)。通过扫描电子显微镜（SEM）和傅立叶变换红外光谱（FTIR）对所获得的纳米生物复合材料进行了研究。通过超声波和 zeta 电位测量，确定了 AgHAp-CH 悬浮液的良好稳定性。此外，还评估了 AgHAp-CH 纳米生物复合材料对金黄色葡萄球菌 ATCC 25923、大肠杆菌 ATCC 25922 和白色念珠菌 ATCC 10231 微生物菌株的抗菌活性。AgHAp-CH 纳米生物复合材料对所研究的微生物菌株具有有效的抗菌效果。考虑到开发这些纳米生物材料所涉及的简便方法及其优异特性，建议将其作为生物医学领域的合适应用候选材料。

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来源期刊

Macromolecular Symposia Materials Science-Polymers and Plastics

CiteScore

1.50

自引率

0.00%

发文量

226

期刊介绍： Macromolecular Symposia presents state-of-the-art research articles in the field of macromolecular chemistry and physics. All submitted contributions are peer-reviewed to ensure a high quality of published manuscripts. Accepted articles will be typeset and published as a hardcover edition together with online publication at Wiley InterScience, thereby guaranteeing an immediate international dissemination.