Homeostatic feeding in hedonic centres

IF 18.9 1区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Zhe Zhao, Sarah A. Stern
{"title":"Homeostatic feeding in hedonic centres","authors":"Zhe Zhao, Sarah A. Stern","doi":"10.1038/s42255-024-01089-6","DOIUrl":null,"url":null,"abstract":"Dopamine D1 receptors of the nucleus accumbens (NAc) can be divided into different transcriptomic subtypes, and are crucial for reward processing and regulating feeding behaviour. One subtype — the NAc SERPINB2+ neuron— is identified as necessary for the specific control of food intake and energy balance, and could serve as a target for addressing obesity and eating disorders.","PeriodicalId":19038,"journal":{"name":"Nature metabolism","volume":null,"pages":null},"PeriodicalIF":18.9000,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature metabolism","FirstCategoryId":"3","ListUrlMain":"https://www.nature.com/articles/s42255-024-01089-6","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0

Abstract

Dopamine D1 receptors of the nucleus accumbens (NAc) can be divided into different transcriptomic subtypes, and are crucial for reward processing and regulating feeding behaviour. One subtype — the NAc SERPINB2+ neuron— is identified as necessary for the specific control of food intake and energy balance, and could serve as a target for addressing obesity and eating disorders.

Abstract Image

Abstract Image

享乐中心的同态饲养
多巴胺多巴核(NAc)的多巴胺 D1 受体可分为不同的转录组亚型,它们对奖赏处理和调节进食行为至关重要。其中一种亚型--NAc SERPINB2+神经元被认为是控制食物摄入和能量平衡所必需的,可作为解决肥胖和饮食失调问题的靶标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Nature metabolism
Nature metabolism ENDOCRINOLOGY & METABOLISM-
CiteScore
27.50
自引率
2.40%
发文量
170
期刊介绍: Nature Metabolism is a peer-reviewed scientific journal that covers a broad range of topics in metabolism research. It aims to advance the understanding of metabolic and homeostatic processes at a cellular and physiological level. The journal publishes research from various fields, including fundamental cell biology, basic biomedical and translational research, and integrative physiology. It focuses on how cellular metabolism affects cellular function, the physiology and homeostasis of organs and tissues, and the regulation of organismal energy homeostasis. It also investigates the molecular pathophysiology of metabolic diseases such as diabetes and obesity, as well as their treatment. Nature Metabolism follows the standards of other Nature-branded journals, with a dedicated team of professional editors, rigorous peer-review process, high standards of copy-editing and production, swift publication, and editorial independence. The journal has a high impact factor, has a certain influence in the international area, and is deeply concerned and cited by the majority of scholars.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信