Evaluation of calculation accuracy and computation time in a commercial treatment planning system for accelerator-based boron neutron capture therapy.

IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Akihiko Takeuchi, Katsumi Hirose, Ryohei Kato, Shinya Komori, Mariko Sato, Tomoaki Motoyanagi, Yuhei Yamazaki, Yuki Narita, Yoshihiro Takai, Takahiro Kato
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引用次数: 0

Abstract

This study aims to evaluate the feasibility of using a commercially available boron neutron capture therapy (BNCT) dose calculation program (NeuCure® Dose Engine) in terms of calculation accuracy and computation time. Treatment planning was simulated under the following calculation parameters: 1.5-5.0 mm grid sizes and 1-10% statistical uncertainties. The calculated monitor units (MUs) and computation times were evaluated. The MUs calculated on grid sizes larger than 2 mm were overestimated by 2% compared with the result of 1.5 mm grid. We established the two-step method for the routine administration of BNCT: multiple calculations involved in beam optimization should be done at a 5 mm grid and a 10% statistical uncertainty (the shortest computation time: 10.3 ± 2.1 min) in the first-step, and final dose calculations should be performed at a 2 mm grid and a 10% statistical uncertainty (satisfied clinical accuracy: 6.9 ± 0.3 h) in the second-step.

评估基于加速器的硼中子俘获疗法商业治疗计划系统的计算精度和计算时间。
本研究旨在评估使用市售硼中子俘获疗法(BNCT)剂量计算程序(NeuCure® Dose Engine)在计算精度和计算时间方面的可行性。在以下计算参数下模拟了治疗规划:网格尺寸为 1.5-5.0 毫米,统计不确定性为 1-10%。对计算出的监测单位(MU)和计算时间进行了评估。与 1.5 毫米网格的结果相比,在大于 2 毫米的网格上计算出的监测单位被高估了 2%。我们为 BNCT 的常规应用制定了两步法:第一步应在 5 毫米网格和 10%统计不确定性(最短计算时间:10.3 ± 2.1 分钟)的条件下进行射束优化所涉及的多次计算,第二步应在 2 毫米网格和 10%统计不确定性(满足临床准确性:6.9 ± 0.3 小时)的条件下进行最终剂量计算。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Radiological Physics and Technology
Radiological Physics and Technology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
3.00
自引率
12.50%
发文量
40
期刊介绍: The purpose of the journal Radiological Physics and Technology is to provide a forum for sharing new knowledge related to research and development in radiological science and technology, including medical physics and radiological technology in diagnostic radiology, nuclear medicine, and radiation therapy among many other radiological disciplines, as well as to contribute to progress and improvement in medical practice and patient health care.
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