Exploring the link between myocardial bridging and left ventricular hypertrophy: Congenital factors or remodelling?

IF 3.7 3区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Kardiologia polska Pub Date : 2024-08-14 DOI:10.33963/v.phj.102044

Burak Acar, Ozgür Cakir, Umut Celikyurt, Ozgür Barıs, Aysegul Durmaz, Ahmet Yalnız, Said Atıs, Beyza Nur Basova, Ercument Ciftci

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引用次数: 0

Abstract

Background: Myocardial bridging (MB) was considered a congenital anomaly and found increased frequency in coronary computed tomography angiography. Some case studies reported the association of MB with various cardiomyopathies. However, the association between MB severity and left ventricular hypertrophy remains unclear. This cross-sectional study aimed to evaluate whether myocardial bridge is related to left ventricular hypertrophy in patients referred for coronary computed tomography angiography (CCTA).

Methods: This cross-sectional study included two hundred and twenty-seven patients (age 53.2 [11.1] years, 48 % female) who underwent 640-slice CCTA and were diagnosed with MB. MB severity was measured as MB muscle index (MMI) (MB length x MB thickness) and, left ventricular hypertrophy (LVH) was assessed with transthoracic echocardiography.

Results: MB segments were detected in all patients on the left anterior descending artery. CCTA was performed to exclude coronary artery disease in most patients (90%, n=206). Eighty-two (36.1 %) had LVH, and MMI was significantly higher in patients with LVH than those without LVH (27.3[19.5-38.9] vs 24 [13.8-37.1], P = 0.022, respectively). There was a positive correlation between the left ventricular mass index and myocardial bridge length (r=0.414, P =0.001), MB index (r=0.310, P <0.001), and the age of the patients (r=0.191, P = 0.004). MB thickness and MMI were also positively correlated with relative wall thickness.

Conclusion: MB is a common finding, and its severity is associated with left ventricular hypertrophy in patients undergoing CCTA.

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探索心肌桥接与左心室肥厚之间的联系：先天因素还是重塑？

背景：心肌桥接（MB）被认为是一种先天性异常，在冠状动脉计算机断层扫描血管造影中被发现的频率越来越高。一些病例研究报告了 MB 与各种心肌病的关系。然而，MB 严重程度与左心室肥厚之间的关系仍不清楚。这项横断面研究旨在评估转诊接受冠状动脉计算机断层扫描血管造影术（CCTA）的患者中，心肌桥与左心室肥厚是否相关：这项横断面研究纳入了 227 名接受 640 片 CCTA 并被诊断为 MB 的患者（年龄 53.2 [11.1] 岁，48% 为女性）。MB 的严重程度以 MB 肌肉指数（MMI）（MB 长度 x MB 厚度）来衡量，并通过经胸超声心动图评估左心室肥厚（LVH）：结果：所有患者的左前降支动脉均检测到 MB 段。大多数患者（90%，n=206）通过 CCTA 检查排除了冠状动脉疾病。82例（36.1%）患者有左心室肥厚，有左心室肥厚患者的MMI明显高于无左心室肥厚患者（分别为27.3[19.5-38.9] vs 24 [13.8-37.1]，P = 0.022）。左心室质量指数与心肌桥长度（r=0.414，P=0.001）、MB指数（r=0.310，P 结论：MB是一种常见的心肌病变，其发病率较高：在接受 CCTA 检查的患者中，MB 是一种常见的发现，其严重程度与左心室肥厚有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Kardiologia polska 医学-心血管系统

CiteScore

3.00

自引率

24.20%

发文量

431

审稿时长

3-6 weeks

期刊介绍： Kardiologia Polska (Kardiol Pol, Polish Heart Journal) is the official peer-reviewed journal of the Polish Cardiac Society (PTK, Polskie Towarzystwo Kardiologiczne) published monthly since 1957. It aims to provide a platform for sharing knowledge in cardiology, from basic science to translational and clinical research on cardiovascular diseases.