Analysis of Risk Factors for Postoperative Deep Vein Thrombosis in Traumatic Spinal Fracture Complicated with Spinal Cord Injury.

IF 2.3 4区 医学 Q2 HEMATOLOGY
Diao Yang, Shiwen Chen, Can Zhuo, Haidan Chen
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Abstract

The purpose of this study is to investigate the risk factors for postoperative deep vein thrombosis (DVT) in patients with traumatic spinal fractures complicated with Spinal Cord Injury(SCI). We conducted a retrospective analysis of 110 patients with traumatic spinal fractures and SCI admitted to our hospital from March 2021 to April 2024. DVT was diagnosed using ultrasound. Patient history, general data, surgical data, laboratory tests, and thromboelastogram (TEG) results were collected. The patients were divided into a DVT group and a non-DVT group according to the results of ultrasound one week after surgery. The risk factors and diagnostic value were analyzed using binary logistic regression and receiver operating characteristic (ROC) curves in both univariate and multivariate analyses. Multivariate and ROC analysis results showed that D-dimer, lower extremity, duration of bedrest, and MA values of TEG were independent risk factors for DVT in SCI, with D-dimer having the highest diagnostic value (AUC = 0.883). The AUC values for lower extremity, duration of bedrest, and MA were 0.731, 0.750, and 0.625. In conclusion, Postoperative D-dimer > 5.065 mg/l, lower extremity < 3, duration of bedrest, and MA value of TEG are independent risk factors for postoperative DVT in SCI patients, D-dimer having the highest diagnostic value. When the above risk factors occur, clinicians need to be vigilant and take appropriate prevention and treatment measures.

创伤性脊柱骨折并发脊髓损伤术后深静脉血栓形成的风险因素分析。
本研究旨在探讨创伤性脊柱骨折并发脊髓损伤(SCI)患者术后深静脉血栓形成(DVT)的风险因素。我们对 2021 年 3 月至 2024 年 4 月期间本院收治的 110 例创伤性脊柱骨折合并 SCI 患者进行了回顾性分析。深静脉血栓是通过超声波诊断的。收集了患者的病史、一般资料、手术资料、实验室检查和血栓弹力图(TEG)结果。根据术后一周的超声波检查结果,将患者分为深静脉血栓组和非深静脉血栓组。在单变量和多变量分析中,使用二元逻辑回归和接收者操作特征曲线(ROC)分析了风险因素和诊断价值。多变量和ROC分析结果显示,D-二聚体、下肢、卧床时间和TEG的MA值是SCI深静脉血栓的独立危险因素,其中D-二聚体的诊断价值最高(AUC = 0.883)。下肢、卧床时间和 MA 的 AUC 值分别为 0.731、0.750 和 0.625。总之,术后 D-二聚体 > 5.065 毫克/升、下肢
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来源期刊
CiteScore
4.40
自引率
3.40%
发文量
150
审稿时长
2 months
期刊介绍: CATH is a peer-reviewed bi-monthly journal that addresses the practical clinical and laboratory issues involved in managing bleeding and clotting disorders, especially those related to thrombosis, hemostasis, and vascular disorders. CATH covers clinical trials, studies on etiology, pathophysiology, diagnosis and treatment of thrombohemorrhagic disorders.
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