Bipolar disorder and oxidative stress: A bibliometric perspective

IF 2.8 3区医学 Q2 PSYCHIATRY

Asia‐Pacific Psychiatry Pub Date : 2024-08-13 DOI:10.1111/appy.12564

Zhen Gui PhD, Qinge Zhang MD, Sha Sha MD, Xiao-Hong Li MD, Zhaohui Su PhD, Teris Cheung PhD, Xi-Ling Cui PhD, Gabor S. Ungvari MD, PhD, Katrine K. Wong PhD, Chee H. Ng MBBS, MD, Feng Yuan MD, Yu-Tao Xiang MD, PhD

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引用次数: 0

Abstract

Objective

Accumulating evidence indicates that oxidative stress and the disruption of antioxidant defenses play an important role in the neurobiology of bipolar disorder (BD). Studies have found that increased oxidative stress may be associated with cell apoptosis and neuronal damage in BD patients. Hence, this study explored the research field related to BD and oxidative stress from a bibliometrics perspective.

Methods

Literature search and relevant data retrieval based on the Web of Sciences Core Collection (WoSCC). R software (version 4.2.2), VOSviewer software (version 1.6.18), and CiteSpace (version 6.1.6) were used in this bibliometric analysis.

Results

A total of 2081 publications related to BD and oxidative stress were published between 1986 and 2024. Bipolar Disorders was the journal that had the most publications in this area (72; 3.46%; IF = 5.9), while the United States (1285; 61.7%) and the University of Toronto (377; 18.1%) were the most productive country and institution, respectively. Apart from “oxidative stress” and “bipolar disorder,” the most frequently used keywords were “schizophrenia,” “prefrontal cortex,” and “nitric oxide.”

Conclusions

The growing number of publications related to BD and oxidative stress in recent years highlights the importance of this research field. Hot topics in research related to BD and oxidative stress included animal experiments and molecular mechanisms, psychiatric-related inflammation and biomarkers, neurodegenerative diseases, and metabolism. Furthermore, the biological mechanisms of BD, particularly biomarkers and inflammation, may be the emerging research priority area in the future.

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查看原文本刊更多论文

躁郁症与氧化应激：文献计量学视角。

目的：越来越多的证据表明，氧化应激和抗氧化防御系统的破坏在双相情感障碍（BD）的神经生物学中起着重要作用。研究发现，氧化应激的增加可能与双相情感障碍患者的细胞凋亡和神经元损伤有关。因此，本研究从文献计量学的角度探讨了与双相情感障碍和氧化应激相关的研究领域：文献检索和相关数据检索基于 Web of Sciences Core Collection (WoSCC)。文献计量学分析使用了 R 软件（4.2.2 版）、VOSviewer 软件（1.6.18 版）和 CiteSpace（6.1.6 版）：结果：1986 年至 2024 年间，共发表了 2081 篇与 BD 和氧化应激相关的论文。双相情感障碍》是该领域发表论文最多的期刊（72篇；3.46%；IF=5.9），而美国（1285篇；61.7%）和多伦多大学（377篇；18.1%）分别是发表论文最多的国家和机构。除 "氧化应激 "和 "双相情感障碍 "外，最常使用的关键词是 "精神分裂症"、"前额叶皮质 "和 "一氧化氮"：近年来，与躁狂症和氧化应激相关的论文数量不断增加，凸显了这一研究领域的重要性。与 BD 和氧化应激相关的研究热点包括动物实验和分子机制、精神相关炎症和生物标志物、神经退行性疾病和新陈代谢。此外，BD 的生物学机制，尤其是生物标志物和炎症，可能是未来新兴的研究重点领域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Asia‐Pacific Psychiatry PSYCHIATRY-

CiteScore

7.80

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Asia-Pacific Psychiatry is an international psychiatric journal focused on the Asia and Pacific Rim region, and is the official journal of the Pacific Rim College of Psychiatrics. Asia-Pacific Psychiatry enables psychiatric and other mental health professionals in the region to share their research, education programs and clinical experience with a larger international readership. The journal offers a venue for high quality research for and from the region in the face of minimal international publication availability for authors concerned with the region. This includes findings highlighting the diversity in psychiatric behaviour, treatment and outcome related to social, ethnic, cultural and economic differences of the region. The journal publishes peer-reviewed articles and reviews, as well as clinically and educationally focused papers on regional best practices. Images, videos, a young psychiatrist''s corner, meeting reports, a journal club and contextual commentaries differentiate this journal from existing main stream psychiatry journals that are focused on other regions, or nationally focused within countries of Asia and the Pacific Rim.