Peucedanol ameliorates LPS-induced inflammation in RAW264.7 cells and CLP-induced sepsis in mice by inhibiting TLR4/myD88/NF-κB pathway

Qi Yao, Bo-tao Chang
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Abstract

Background Previously, it has reported that Peucedanol (PEU) possesses anti-bacterial activity. However, its effect and mechanism against inflammation remains unclear.
牡丹醇通过抑制 TLR4/myD88/NF-κB 通路,改善 LPS 诱导的 RAW264.7 细胞炎症和 CLP 诱导的小鼠败血症
背景 以前曾有报道称,牡荆醇(PEU)具有抗菌活性。然而,其抗炎效果和机制仍不清楚。
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