C. Valach, Emiel F. M. Wouters, A. Ofenheimer, P. Pompilio, Alessandro Gobbi, M. Breyer, Sylvia Hartl, C. Veneroni, T. Mraz, C. Schiffers, O. C. Burghuber, Ahmad Karimi, Christoph Gross, Charles G. Irvin, R. Breyer-Kohansal
{"title":"Oscillometry Reference Values for Children and Adolescents","authors":"C. Valach, Emiel F. M. Wouters, A. Ofenheimer, P. Pompilio, Alessandro Gobbi, M. Breyer, Sylvia Hartl, C. Veneroni, T. Mraz, C. Schiffers, O. C. Burghuber, Ahmad Karimi, Christoph Gross, Charles G. Irvin, R. Breyer-Kohansal","doi":"10.1183/23120541.00278-2024","DOIUrl":null,"url":null,"abstract":"Oscillometry devices allow quantification of respiratory function at tidal breathing but device-specific reference equations are scarce: the present study aims to create sex-specific oscillometric reference values for children and adolescents using the Resmon PRO FULL device.Healthy participants (N=981) aged 6 to 17 years of the Austrian LEAD general population cohort were included. Subjects had normal weight (BMI≤99th percentile) and normal lung volumes (total lung capacity (TLC)≥lower limit of normal). Oscillometry data were collected using a single frequency mode of 8 Hz. Sex-specific prediction equations were developed for total (tot), inspiratory (insp) and expiratory (exp) resistance (R) and reactance (X) as well as for the modulus of impedance (Z) value using the LMS (lambda, mu, sigma) method. Height was used as a single covariate.Reference equations for all oscillometry parameters were created for Caucasian children aged 6 to 17 years with a height span from 101 to 183 cm and a lung volume span from 1.7 L to 8.8 L TLC. R and Z values progressively decrease and X values increase with increasing height. Oscillometry parametersversuslung volume curves differ from thoseversusheight curves. Stratified for lung size, no sex differences are found for oscillometry parameters.Our study provides reference values for oscillometry parameters in children and adolescents using strictly defined criteria for weight and lung volumes. No sex related differences in oscillometry parameters corrected for height or lung size are found.","PeriodicalId":11739,"journal":{"name":"ERJ Open Research","volume":null,"pages":null},"PeriodicalIF":4.3000,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ERJ Open Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1183/23120541.00278-2024","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
引用次数: 0
Abstract
Oscillometry devices allow quantification of respiratory function at tidal breathing but device-specific reference equations are scarce: the present study aims to create sex-specific oscillometric reference values for children and adolescents using the Resmon PRO FULL device.Healthy participants (N=981) aged 6 to 17 years of the Austrian LEAD general population cohort were included. Subjects had normal weight (BMI≤99th percentile) and normal lung volumes (total lung capacity (TLC)≥lower limit of normal). Oscillometry data were collected using a single frequency mode of 8 Hz. Sex-specific prediction equations were developed for total (tot), inspiratory (insp) and expiratory (exp) resistance (R) and reactance (X) as well as for the modulus of impedance (Z) value using the LMS (lambda, mu, sigma) method. Height was used as a single covariate.Reference equations for all oscillometry parameters were created for Caucasian children aged 6 to 17 years with a height span from 101 to 183 cm and a lung volume span from 1.7 L to 8.8 L TLC. R and Z values progressively decrease and X values increase with increasing height. Oscillometry parametersversuslung volume curves differ from thoseversusheight curves. Stratified for lung size, no sex differences are found for oscillometry parameters.Our study provides reference values for oscillometry parameters in children and adolescents using strictly defined criteria for weight and lung volumes. No sex related differences in oscillometry parameters corrected for height or lung size are found.
期刊介绍:
ERJ Open Research is a fully open access original research journal, published online by the European Respiratory Society. The journal aims to publish high-quality work in all fields of respiratory science and medicine, covering basic science, clinical translational science and clinical medicine. The journal was created to help fulfil the ERS objective to disseminate scientific and educational material to its members and to the medical community, but also to provide researchers with an affordable open access specialty journal in which to publish their work.