O uso de metronidazol em feridas neoplásicas malignas de pacientes sob cuidados paliativos em uma instituição pública no Distrito Federal, Brasil

Espaço para a Saúde - Revista de Saúde Pública do Paraná Pub Date : 2024-08-09 DOI:10.22421/1517-7130/es.2024v25.e1009

Laís Manuela Borges Ribeiro, Diel Gomes da Silva Junior, Alliny do Nascimento Martins, Emília Vitória da Silva, Debora Cristyna Ferreira Reis

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Abstract

Palliative care (PC) is essential for oncology patients, especially those with malignant neoplastic wounds (MNW) that produce unpleasant odor, causing impacts such as vomiting and social isolation. Metronidazole is often used off-label to treat this symptom. This descriptive, cross-sectional study investigated the profile of patients who received metronidazole for odor control in MNW and evaluated the benefits of this treatment. Conducted from January 2018 to December 2022 at a CP reference hospital in the Federal District, with patients admitted to the oncology ward for palliative care, retrospective chart analysis revealed that 87.04% of patients benefited from the medication. Head and neck cancer was the predominant diagnosis among the 30 patients included, 17 of whorm were men (56.67%). The study demonstrates consistent improvements in odor control in MNW with the use of metronidazole, reinforcing its efficacy in this specific clinical context.

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甲硝唑在巴西联邦区一家公立机构接受姑息治疗的恶性肿瘤患者伤口中的应用

姑息治疗（PC）对肿瘤患者至关重要，尤其是那些患有恶性肿瘤伤口（MNW）的患者，这些伤口会产生难闻的气味，造成呕吐和社交孤立等影响。甲硝唑常被用于治疗这一症状。这项描述性横断面研究调查了接受甲硝唑治疗以控制MNW气味的患者情况，并评估了这种治疗方法的益处。该研究于2018年1月至2022年12月在联邦区一家CP参考医院进行，研究对象为肿瘤病房收治的姑息治疗患者，回顾性病历分析显示，87.04%的患者从药物治疗中获益。在纳入的 30 名患者中，头颈部癌症是主要诊断，其中 17 人为男性（56.67%）。该研究表明，使用甲硝唑后，多发性骨髓瘤患者的气味控制情况得到了持续改善，从而巩固了甲硝唑在这一特殊临床环境中的疗效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Espaço para a Saúde - Revista de Saúde Pública do Paraná

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