Urinary tract infections in chronic kidney disease in Nephrology unit, University Hospital Center of Befelatanana, Antananarivo.

Q3 Medicine

Tunisie Medicale Pub Date : 2024-08-05 DOI:10.62438/tunismed.v102i8.4830

Mihary Dodo, Faniry Notahiantsoa Ratrimoharilala, Benja Ramilitiana, Catherine Razafindrakoto, Nomenjanahary Andriniaina Rakotoarisoa, Lova Narindra Randriamanantsoa, Harilalaina Willy Franck Randriamarotia

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Abstract

Introduction: Urinary tract infection is the leading cause of nosocomial infection worldwide. It is a factor in the progression of chronic kidney disease.

Aim: To determine the epidemiological, clinical, microbiological, therapeutic and evolving profile of patients with chronic kidney disease and urinary tract infection.

Methods: This was a retrospective, descriptive study lasting 5 years, from January 2014 to december 2018 in chronic kidney disease with urinary tract infection.

Results: Fifty-one patients (7.15%) were retained with a mean age of 53.03 years and a sex ratio of 0.55. Chronic kidney disease was in end-stage in 45.1% (n=23). Cystitis was found in 49.02% (n=25) and gram-negative bacilli were found in 74.50% (n=38), predominantly Escherichia coli (54.90%). Third generation of cephalosporins and fluoroquinolones were frequently prescribed as probabilistic antibiotics. Resistance to beta-lactam antibiotics was 50% for Escherichia coli. Factors influencing severe infection were: advanced age, male gender, urinary lithiasis, multiple antibiotic resistance and non-enterobacterial germs.

Conclusion: Urinary tract infection in chronic kidney disease were frequent and particularly severe.

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塔那那利佛贝费拉塔纳纳大学医院中心肾科慢性肾病患者的尿路感染。

导言：尿路感染是全球范围内引起医院内感染的主要原因。目的：确定慢性肾脏病合并尿路感染患者的流行病学、临床、微生物学、治疗和发展概况：这是一项回顾性、描述性研究，从2014年1月至2018年12月，历时5年，研究对象为慢性肾脏病合并尿路感染患者：留观患者51例（7.15%），平均年龄53.03岁，性别比为0.55。45.1%的患者（23 人）处于慢性肾病晚期。膀胱炎患者占 49.02%（25 人），革兰氏阴性杆菌占 74.50%（38 人），主要是大肠埃希菌（54.90%）。第三代头孢菌素和氟喹诺酮类药物经常作为概率抗生素处方。50%的大肠埃希菌对β-内酰胺类抗生素产生耐药性。影响严重感染的因素包括：高龄、男性、尿路结石、多种抗生素耐药和非肠道细菌：结论：慢性肾脏病患者的尿路感染很常见，而且特别严重。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tunisie Medicale Medicine-Medicine (all)

CiteScore

1.00

自引率

0.00%

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