Novel Antibiotics for Urinary Tract Infection (UTI): The EAGLE 2 and EAGLE-3 Trials for Uncomplicated UTI, and the CERTAIN-1 Trial for Complicated UTI.

IF 5.4 3区材料科学 Q2 CHEMISTRY, PHYSICAL

ACS Applied Energy Materials Pub Date : 2024-08-06 DOI:10.1016/j.euf.2024.07.014

Florian Wagenlehner

引用次数: 0

Abstract

Two novel antibiotics have been evaluated for the treatment of urinary tract infection (UTI). Gepotidacin was an efficacious first-in-class oral antibiotic in uncomplicated UTI in comparison to nitrofurantoin. Cefepime/taniborbactam was superior to meropenem in complicated UTI and acute pyelonephritis.

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治疗尿路感染 (UTI) 的新型抗生素：针对非复杂性 UTI 的 EAGLE 2 和 EAGLE-3 试验，以及针对复杂性 UTI 的 CERTAIN-1 试验。

对治疗尿路感染（UTI）的两种新型抗生素进行了评估。与硝基呋喃妥因相比，开博他星是治疗无并发症UTI的第一种有效口服抗生素。在复杂性UTI和急性肾盂肾炎中，头孢吡肟/他尼巴坦优于美罗培南。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Energy Materials Materials Science-Materials Chemistry

CiteScore

10.30

自引率

6.20%

发文量

1368

期刊介绍： ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.