Frequency and Associated Factors of Venous Thromboembolism in Cervical Spine Surgery.

IF 1.7 Q2 SURGERY

International Journal of Spine Surgery Pub Date : 2024-08-06 DOI:10.14444/8624

Masashi Uehara, Shota Ikegami, Hiroki Oba, Yoshinari Miyaoka, Terue Hatakenaka, Daisuke Kurogochi, Shinji Sasao, Tetsuhiko Mimura, Jun Takahashi

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引用次数: 0

Abstract

Background: Venous thromboembolism (VTE) is a well-known complication after spine surgery. As many cases of cervical spine disease result in severe gait disturbance due to myelopathy, it may harbor a higher risk of VTE than other spinal disorders. However, few studies have focused primarily on cervical spine surgery to date. This investigation sought to determine the prevalence of VTE after cervical spine surgery and identify patient-based risk factors.

Methods: The medical data of 341 consecutive patients (240 men and 101 women; mean age, 68.1 years) who underwent cervical spine surgery were retrospectively examined. Logistic regression models were employed to examine the prevalence, characteristics, and risk factors of postoperative VTE.

Results: In this study, 2.6% of cervical spine surgery patients experienced postoperative VTE. In comparisons of VTE and non-VTE groups, significant differences were found for age (79.6 years vs 67.7 years, P < 0.01), 1-week postoperative D-dimer level (10.6 μg/mL vs 2.7 μg/mL, P < 0.01), and cardiovascular disease (44.4% vs 11.1%, P = 0.011). Multivariate analysis identified elevated postoperative D-dimer level and cardiovascular disease as significantly associated with postsurgical VTE with respective odds ratios of 1.54 and 9.52.

Conclusion: Postoperative VTE in cervical spine surgery was seen in 2.6% of cases. Patients with elevated postoperative D-dimer level and cardiovascular disease may be at increased risk of VTE and may require additional observation.

Clinical relevance: Spine surgeons should take into account that patients with elevated postoperative D-dimer levels and cardiovascular disease may be at increased risk for VTE.

Level of evidence: 4:

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颈椎手术中静脉血栓栓塞症的发生率及相关因素

背景：众所周知，静脉血栓栓塞症（VTE）是脊柱手术后的一种并发症。由于许多颈椎病患者会因脊髓病变而导致严重的步态障碍，因此与其他脊柱疾病相比，颈椎病可能蕴含着更高的 VTE 风险。然而，迄今为止很少有研究主要关注颈椎手术。本调查旨在确定颈椎手术后 VTE 的发生率，并识别基于患者的风险因素：回顾性研究了连续接受颈椎手术的 341 名患者（男性 240 人，女性 101 人；平均年龄 68.1 岁）的医疗数据。采用逻辑回归模型研究了术后 VTE 的发生率、特征和风险因素：结果：在这项研究中，2.6% 的颈椎手术患者在术后出现了 VTE。在 VTE 组和非 VTE 组的比较中发现，年龄（79.6 岁 vs 67.7 岁，P < 0.01）、术后 1 周 D-二聚体水平（10.6 μg/mL vs 2.7 μg/mL，P < 0.01）和心血管疾病（44.4% vs 11.1%，P = 0.011）存在显著差异。多变量分析发现，术后 D-二聚体水平升高和心血管疾病与术后 VTE 显著相关，各自的几率分别为 1.54 和 9.52：颈椎手术术后 VTE 发生率为 2.6%。术后 D-二聚体水平升高且患有心血管疾病的患者发生 VTE 的风险可能会增加，因此可能需要额外观察：脊柱外科医生应考虑到术后 D-二聚体水平升高和心血管疾病患者可能会增加 VTE 风险：4:

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Spine Surgery Medicine-Surgery

CiteScore

3.10

自引率

0.00%

发文量

162

期刊介绍： The International Journal of Spine Surgery is the official scientific journal of ISASS, the International Intradiscal Therapy Society, the Pittsburgh Spine Summit, and the Büttner-Janz Spinefoundation, and is an official partner of the Southern Neurosurgical Society. The goal of the International Journal of Spine Surgery is to promote and disseminate online the most up-to-date scientific and clinical research into innovations in motion preservation and new spinal surgery technology, including basic science, biologics, and tissue engineering. The Journal is dedicated to educating spine surgeons worldwide by reporting on the scientific basis, indications, surgical techniques, complications, outcomes, and follow-up data for promising spinal procedures.