The chromolinker hypothesis: Are eukaryotic genomes also circular?

IF 2 4区生物学 Q2 BIOLOGY

Biosystems Pub Date : 2024-08-07 DOI:10.1016/j.biosystems.2024.105280

Richard Gordon

引用次数: 0

Abstract

Over more than the past century, reports that chromosomes in Eukaryotes are linked have been published. Recently this has been confirmed by micromanipulation. The chromolinkers are DNAse sensitive, as has been previously reported. The arguments for and against chromolinkers have been reviewed, and a call for definitive research made, because if chromolinkers do exist, the whole basis for ~~nuclear DNA~~ genetics may require revision.

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染色单体假说：真核生物基因组也是环状的吗？

在过去的一个多世纪里，关于真核生物染色体相连的报道屡见报端。最近，微操作证实了这一点。正如之前所报道的，染色单体对 DNAse 敏感。我们回顾了支持和反对染色单体的论点，并呼吁进行明确的研究，因为如果染色单体真的存在，那么核 DNA 遗传学的整个基础可能需要修改。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biosystems 生物-生物学

CiteScore

3.70

自引率

18.80%

发文量

129

审稿时长

34 days

期刊介绍： BioSystems encourages experimental, computational, and theoretical articles that link biology, evolutionary thinking, and the information processing sciences. The link areas form a circle that encompasses the fundamental nature of biological information processing, computational modeling of complex biological systems, evolutionary models of computation, the application of biological principles to the design of novel computing systems, and the use of biomolecular materials to synthesize artificial systems that capture essential principles of natural biological information processing.