{"title":"Cardiac Arrest Due to Capecitabine Toxicosis Treated With ECMO and CRRT: A Case Report.","authors":"Liqin Zhang, Mingjun Liu, Lutao Xie, Xin Tian","doi":"10.4037/ccn2024858","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>This is the first report of a patient who developed cardiogenic shock after receiving oral chemotherapy with capecitabine and was treated with venoarterial extracorporeal membrane oxygenation combined with continuous renal replacement therapy.</p><p><strong>Clinical findings: </strong>A 58-year-old man developed an arrhythmia that rapidly progressed to cardiogenic shock and cardiac arrest after receiving oral capecitabine tablets to treat a rectal malignancy.</p><p><strong>Interventions: </strong>The patient was treated with venoarterial extracorporeal membrane oxygenation in combination with continuous renal replacement therapy.</p><p><strong>Outcome: </strong>The patient made a full recovery and was discharged from the hospital.</p><p><strong>Conclusion: </strong>The use of comprehensive supportive treatments such as extracorporeal membrane oxygenation combined with continuous renal replacement therapy in patients with capecitabine-induced cardiac arrest can rapidly reduce drug concentrations, eliminate harmful substances, and improve the prognosis.</p>","PeriodicalId":10738,"journal":{"name":"Critical care nurse","volume":"44 4","pages":"57-62"},"PeriodicalIF":2.0000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Critical care nurse","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4037/ccn2024858","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: This is the first report of a patient who developed cardiogenic shock after receiving oral chemotherapy with capecitabine and was treated with venoarterial extracorporeal membrane oxygenation combined with continuous renal replacement therapy.
Clinical findings: A 58-year-old man developed an arrhythmia that rapidly progressed to cardiogenic shock and cardiac arrest after receiving oral capecitabine tablets to treat a rectal malignancy.
Interventions: The patient was treated with venoarterial extracorporeal membrane oxygenation in combination with continuous renal replacement therapy.
Outcome: The patient made a full recovery and was discharged from the hospital.
Conclusion: The use of comprehensive supportive treatments such as extracorporeal membrane oxygenation combined with continuous renal replacement therapy in patients with capecitabine-induced cardiac arrest can rapidly reduce drug concentrations, eliminate harmful substances, and improve the prognosis.
期刊介绍：
Critical Care Nurse (CCN) is an official publication of the American Association of Critical-Care Nurses (AACN). Authors are invited to submit manuscripts for consideration and peer review. Clinical topics must meet the mission of CCN and address nursing practice of acute and critically ill patients.
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